Sökning: "gastrointestinal model"

Visar resultat 1 - 5 av 128 avhandlingar innehållade orden gastrointestinal model.

  1. 1. Psychological responses to gastrointestinal cancer

    Författare :Karin Nordin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Gastrointestinal cancer; coping; anxiety; depression; subjectivedistress; prediction; psychometric analysis; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : The overall aim of the present thesis is to gain knowledge about psychological distress and adjustment in gastrointestinal cancer patients (colon, rectum, gastric, pancreatic or biliary) at various phases of their disease.Reactions to the diagnosis, anxiety, depression and coping were investigated in newly diagnosed patients (n=139). LÄS MER

  3. 2. Pharmacokinetic and pharmacodynamic analysis of antidiuretic peptides

    Författare :Torbjörn Callréus; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lithium; indirect-response model; pharmacodynamics; pharmacokinetics; gastrointestinal absorption; gastrointestinal motility; loperamide; erythromycin; antidiuretic effect; desmopressin; overhydration; vasopressin analogue F992 ; interaction; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : The clinical pharmacology of desmopressin and a new vasopressin analogue (F992) was investigated in healthy human subjects. The common procedure of overhydration of healthy volunteers when studying the antidiuretic effect of a drug, may affect the pharmacokinetics, in particular the volumes of distribution. LÄS MER

  4. 3. Migraine comorbidities : Associations with psychiatric and gastrointestinal disorders

    Författare :Nike Welander; Jessica Mwinyi; Mattias Linde; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Migraine; Comorbidity; Psychiatric disorders; Gastrointestinal disorders; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Migraine is a prevalent neurological disorder with a complex pathophysiology. One factor that potentially complicates migraine treatment is comorbidity between migraine and other disorders, including psychiatric and gastrointestinal disorders. LÄS MER

  5. 4. Chemoradiation in Gastrointestinal Cancer

    Författare :Adalsteinn Gunnlaugsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biliary tract cancer; capecitabine; cholangiocarcinoma; chemoradiation; colon cancer; enteritis 5-fluorouracil; gallbladder cancer; oxaliplatin; pancreatic cancer; rectal cancer.;

    Sammanfattning : Locally advanced inextirpable gastrointestinal cancer has poor prognosis and is associated with high morbidity. One treatment option is to use radiotherapy, often combined with chemotherapy (chemoradiation), either as preoperative treatment to facilitate surgery or in the palliative setting to relieve symptoms. LÄS MER

  7. 5. Oxidation of marine oils during in vitro gastrointestinal digestion and its effects on stress in human intestinal Caco-2 cells

    Författare :Cecilia Tullberg; Chalmers tekniska högskola; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; lipid oxidation; human digestive fluids; LC n-3 PUFAs; Caco-2 cells; marine oils; HNE; MDA; in vitro digestion; HHE; gastrointestinal; aldehydes;

    Sammanfattning : Marine oils are attracting public interest due to the preventive effects, e.g., on inflammation, which are linked to the long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs). However, LC n-3 PUFAs are highly susceptible to oxidation, which could interfere with their positive effects. LÄS MER