Sökning: "gastric adenocarcinoma"

Visar resultat 6 - 10 av 55 avhandlingar innehållade orden gastric adenocarcinoma.

  1. 6. Towards improved oncological treatment of esophageal and gastric cancer. Clinical and translational studies

    Författare :David Borg; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal adenocarcinoma; Gastric cancer; PODXL; Prognosis; Prediction; Chemotherapy dose intensity; Dysphagia; Radiotherapy;

    Sammanfattning : BackgroundThe overall aim of this thesis was to improve the oncological treatment strategies in esophageal and gastric adenocarcinoma (EGAC). Podocalyxin-like protein 1 (PODXL) has been associated with poor prognosis in other cancers and we wanted to investigate its potential role as a prognostic and predictive biomarker in resectable EGAC. LÄS MER

  3. 7. Factors related to the occurrence of gastric adenocarcinoma subtypes

    Författare :Anna Mia Ekström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :gastric; cancer; incidence; trend; cardia; Laurén; histologic; misclassification; antioxidant; completeness; vegetable; fruit; occupation; phenoxy; metal; forestry; Helicobacter pylori; smoking;

    Sammanfattning : Gastric cancer is the second most common cancer worldwide, but the etiology remains poorly understood. A spontaneous global decline has reduced the number of victims in most Western countries while Japan and China have screening programs in place due to the magnitude, and the serious prognosis, of this malignant disease. LÄS MER

  4. 8. Estrogen in the development of esophageal and gastric adenocarcinoma

    Författare :Evangelos Chandanos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis was to address the hypothesis that estrogen protects women against the development of esophageal and gastric adenocarcinoma (AC). These two cancers show a striking but totally unexplained male predominance in their incidence. LÄS MER

  5. 9. Sex hormones in gastric mucosal physiology and the development of oesophageal, gastric and colorectal adenocarcinoma

    Författare :Richard Shore; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis was to continue to test the hypothesis that sex hormones play some part in the aetiology and seem to protect women from the development of oesophageal, gastric, and colorectal adenocarcinoma. All three of these cancers display an as yet unexplained male predominance in their respective worldwide incidence rates. LÄS MER

  7. 10. Helicobacter pylori associated effects on inflammatory radical formation and angiotensin II receptors in the stomach

    Författare :Anders Elfvin; Göteborgs universitet; []
    Nyckelord :Helicobacter pylori; Mongolian gerbil; gastric adenocarcinoma; nitro-radical; iNOS; nitric oxide; nitrotyrosine; oxy-radical; myeloperoxidase; angiotensin II; AT1R; AT2R;

    Sammanfattning : Helicobacter pylori infection of the stomach always results in mucosal inflammation and a marked systemic immune response. Despite the profound host defence reactions the bacterium avoids elimination and persists in the mucosa. This results in chronic inflammation and an increased risk for peptic ulcers and adenocarcinoma. LÄS MER