Sökning: "gamma knife radiosurgery"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden gamma knife radiosurgery.

1. 1. Contouring & planning variability in stereotactic radiosurgery : How to assess and address the weakest link in stereotactic radiosurgery?

   Författare :Helena Sandström; Iuliana Toma-Dasu; David Schlesinger; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; stereotactic radiosurgery; contouring variability; robust treatment planning; Medical Radiation Physics; medicinsk strålningsfysik;

   Sammanfattning : The use of stereotactic radiosurgery (SRS) employing one or a few fractions of high doses of radiation has continuously increased due to the technical development in dose delivery and morphological and functional imaging. As the target volume in SRS is usually defined without margins, the treatment success critically depends on accurate definition and contouring of the target volume and organs at risk (OARs) which are commonly situated in the proximity of the target making their precise delineation particularly important in order to limit possible normal tissue complications. LÄS MER

3. 2. Treatment selection in metastatic renal cell carcinoma : Towards an individualised approach

   Författare :Maria Stenman; Magnus Lindskog; Ulrika Harmenberg; Tim Eisen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rcc; renal cell carcinoma; kidney cancer; stereotactic radiotherapy; srt; stereotactic body radiotherapy; sbrt; gamma knife radiosurgery; gkrs; stereotactic radiosurgery; srs; radiotherapy; overall survival; prognostic factor; papillary; Oncology; Onkologi;

   Sammanfattning : Renal cell carcinoma (RCC), a common malignancy worldwide, affects 1200 new patients yearly in Sweden. Metastatic RCC (mRCC) develops in one in three and is commonly incurable. Clear cell histology dominates followed by papillary histology. LÄS MER

4. 3. Gamma knife surgery of cerebral arteriovenous malformations

   Författare :Bengt Karlsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Brain arteriovenous malformation; Radiosurgery; Natural course; Surgery; Risk; Complications; Prediction; Risk estimation formula; Radionecrosis;

   Sammanfattning : Aims of the study: to define and quantify parameters of importance for the treatment result in Gamma Knife (GK) surgery of arteriovenous malformations (AVM). To determine the natural course of AVM in order to calculate the impact of the GK treatment on the latency period between treatment and obliteration. LÄS MER

5. 4. Contouring variability in radiosurgery - dosimetric and radiobiological implications

   Författare :Helena Sandström; Iuliana Toma-Dasu; Mike Partridge; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Medical Radiation Physics; medicinsk strålningsfysik;

   Sammanfattning : The use of Stereotactic Radiation Therapy (SRT) employing one large fraction of radiation, as in stereotactic radiosurgery (SRS), or few fractions of high doses, has continuously increased due to the technical development and the progress in dose delivery complemented by the positive clinical experience. The success of stereotactic radiation therapy depends on many clinical, dosimetric and radiobiological factors. LÄS MER

7. 5. Volume determination and predictive models in the management of cerebral arteriovenous malformations

   Författare :Michael Söderman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cerebral arteriovenous malformation; Radiosurgery; Embolisation; therapeutic; Outcome assessment;

   Sammanfattning : Cerebral arteriovenous malformations (AVMs) entail a high cumulative risk of severe neurological symptoms and are usually treated with surgery, radiosurgery, embolisation or combinations thereof. There are well supported models to predict the outcome of radiosurgery, but similar models do not exist for surgery or embolisation. LÄS MER