Sökning: "gallstones"

Visar resultat 16 - 19 av 19 avhandlingar innehållade ordet gallstones.

  1. 16. Antibiotic prophylaxis and infectious complications in surgery for acute cholecystitis

    Författare :Gona Jaafar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The prevalence of gallstone disease in the world is 10-20%. Almost 20% of those with gallstone disease develop a complication during their lifetime. Acute cholecystitis (AC) is a common complication of gallstones, that is routinely managed with cholecystectomy. LÄS MER

  3. 17. Gallbladder and pancreatic disease in patients with primary sclerosing cholangitis

    Författare :Karouk Said; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cholecystitis; gallbladder; ejection fraction; magnetic resonance imaging; pancreatic duct; chronic pancreatitis; thioredoxin; Immunohistochemical staining;

    Sammanfattning : The aims of this study were to assess the occurrence of gallbladder abnormalities and dysfunction, to evaluate clinically useful biomarkers for premalignancy and malignancy in gallbladder epithelium and to assess presence of pancreatic duct changes and early pancreatic abnormalities in patients with primary sclerosing cholangitis (PSC). In paper I and III we investigated presence of gallbladder abnormalities in 286 patients with PSC treated at Karolinska University Hospital, Huddinge, between 1970 and 2005. LÄS MER

  4. 18. Understanding the molecular mechanisms of bile acid receptor activation for the treatment of human liver disease

    Författare :Samer Al-Dury; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinska sjukdomar; Gastroenterologi och hepatologi; FXR; IBAT; Gallsyror; Obesitas; Gallstenar;

    Sammanfattning : Farnesoid X receptor (FXR) is a nuclear transcription factor that is activated by bile acids and regulates bile acid homeostasis, glucose and lipid metabolism. FXR activation by a ligand has been identified as a therapeutic modality for a range of liver and metabolic diseases. LÄS MER

  5. 19. Genetic and environmental aspects of symptomatic gallstone disease

    Författare :Despina S Katsika; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Gallstone; Swedish Twin Registry; monozygotic; dizygotic; structural equation modeling; body mass index; alcohol; tobacco; ABCG8 D19 H; lith genes; association study;

    Sammanfattning : Gallstone disease (GD) represents a major healthcare problem. Gallstones are likely to result from a complex interaction of the environment and the effects of multiple undetermined genes. LÄS MER