Sökning: "fysiologiska funktioner"

Visar resultat 1 - 5 av 40 avhandlingar innehållade orden fysiologiska funktioner.

  1. 1. Origin, release and functional significance of the novel gastric hormone ghrelin

    Författare :Charlotta Dornonville de la Cour; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; pharmacognosy; pharmacy; Pharmacological sciences; bone metabolism; energy homeostasis; glucagon; insulin; secretion; pancreastatin; somatostatin; histamine; gastrin; gastric acid secretion; ghrelin; gastric motility; A-like cells; farmakognosi; farmaci; toxikologi;

    Sammanfattning : The novel gastric hormone ghrelin was discovered by virtue of its ability to release growth hormone (GH) via interaction with the so-called GH-secretagogue receptor (GHS-R). Earlier only synthetic agents were known to bind with the GHS-R, hence, ghrelin is the first identified endogenous ligand. LÄS MER

  3. 2. Development of sensitive cellular assay systems and their application to the identification of "orphan" seven-transmembrane receptors

    Författare :Knut Kotarsky; Slemhinnans immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biokemi; Metabolism; Biochemistry; metabolism; leukotrieneB4; thiazolidinedione; 9-HODE; fatty acid; luciferase; GFP; reporter gene; preclinical assay; receptor; GPCR;

    Sammanfattning : Seven-transmembrane, G-protein coupled receptors play a central role in physiology since they facilitate cell communication in multicellular organisms by recognition of a broad range of ligands. They also represent important drug targets. LÄS MER

  4. 3. Monoamine transporters in female human reproduction

    Författare :Barbara Bottalico; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PMAT; VMAT2; OCT; NET; in-situ hybridization histochemistry; decidualization; human endometrium; placenta; Medicine human and vertebrates ; Monoamine transporters; preeclampsia; histamine; Medicin människa och djur ;

    Sammanfattning : The present study explored the gene and protein expression of the monoamine transporters in human endometrium throughout the menstrual cycle, in early decidua and in placentas from normal as well as preeclamptic pregnancies using in-situ hybridization, real time-PCR, immunohistochemistry and primary tissue cultures. Four distinguishable patterns were observed in the endometrium over the menstrual cycle: (1) epithelial expression of norepinephrine transporter (NET) mRNA, (2) Stromal co- expression of vesicular monoamine transporter 2 (VMAT2) and plasma membrane monoamine transporter (PMAT) mRNAs with maximal intensity in the proliferative phase; (3) increasing epithelial expression of VMAT2 mRNA with a maximum in the late secretory phase; (4) stromal expression of extra-neuronal monoamine transporter (EMT) mRNA with a peak in the early secretory phase. LÄS MER

  5. 4. Light Rhythms : Exploring the Perceptual and Behavioural Effects of Daylight and Artificial Light Conditions in a Scandinavian Context

    Författare :Federico Favero; Roberto Bresin; Arne Lowden; Ute Besenecker; Sergio Altomonte; KTH; []
    Nyckelord :HUMANIORA; HUMANITIES; HUMANIORA; HUMANITIES; NATURVETENSKAP; NATURAL SCIENCES; Lighting design; Context; Light; Behaviour; Perception of light; Perception of time; Associative aspects; Architecture; Daylight; Media Technology; Medieteknik;

    Sammanfattning : This compilation thesis collects multidisciplinary work on the study of the impact of light rhythms on perception and behaviour. The thesis was structured to answer and discuss the questions: “How does a person feel and behave inan illuminated space?” and “Do variable light conditions influence perception, appraisal and motion?”. LÄS MER

  7. 5. Selenium Compounds in Milk. Studies of Selenoproteins, Selenium Enrichment and Oxidative Stability of Food

    Författare :Tien Hoac; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; metabolism; Biokemi; Metabolism; Biochemistry; Naturvetenskap; Natural science; Copper; Zinc; Oxidative stability; Thioredoxin reductase; Glutathione peroxidase; Selenoproteins; Milk; Selenium supplementation; Technological sciences; Teknik;

    Sammanfattning : Selenium is an essential nutrient and in animals and humans it can either be specifically incorporated into proteins as selenocysteine or randomly as selenomethionine. It can also occur as low-molecular-weight compounds and the form of selenium in foods may also influence food quality. LÄS MER