Sökning: "fusion proteins"
Visar resultat 16 - 20 av 270 avhandlingar innehållade orden fusion proteins.
16. Functional characterization of the liopsarcoma-associated fusion oncigene FUS-DDIT3
Sammanfattning : Fusion genes represent a growing class of translocation-derived potent oncogenes that frequently show tumor type-specific expression. We have studied the myxoid/round cell liposarcoma (MLS/RCLS)-specific FUS-DDIT3 fusion, with the aim of functionally characterizing this fusion oncogene in sarcoma development. LÄS MER
17. Membrane-mimetic systems : Novel methods and results from studies of respiratory enzymes
Sammanfattning : The processes localized to biological membranes are of great interest, both from a scientific and pharmaceutical point of view. Understanding aspects such as the detailed mechanism and regulation of these processes requires investigation of the structure and function of the membrane-bound proteins in which they take place. LÄS MER
18. Labeling, tagging and charging - Long standing issues in bioenergetics addressed with novel techniques
Sammanfattning : Understanding the molecular details of bioenergetic processes is fundamentally important. Defects in the mitochondrial energy metabolism can lead to untimely apoptosis and thus cause serious degenerative human diseases. LÄS MER
19. Electron crystallography of soluble proteins
Sammanfattning : Protein structures at moderate to high resolution can now be readily solved using an electron microscope and image processing techniques. The averaging conditions required to overcome the low signal to noise ratio of electron microscope images are particularly well satisfied by two-dimensional crystals. LÄS MER
20. Rational and combinatorial genetic engineering approaches for improved recombinant protein production and purification
Sammanfattning : The bacterium Escherichia coli (E. coli) is in many situations an ideal host for production of recombinant proteins, since it generally provides a rapid and economical means to achieve sufficiently high product quantities. LÄS MER