Sökning: "fusidic acid"

Visar resultat 11 - 12 av 12 avhandlingar innehållade orden fusidic acid.

  1. 11. Structural and Biochemical Studies of Antibiotic Resistance and Ribosomal Frameshifting

    Författare :Yang Chen; Maria Selmer; Dominique Fourmy; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein synthesis; elongation; elongation factor G; fusidic acid; antibiotic resistance; aminoglycoside adenyltransferase; ribosomal frameshifting; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Sammanfattning : Protein synthesis, translation, performed by the ribosome, is a fundamental process of life and one of the main targets of antibacterial drugs. This thesis provides structural and biochemical understanding of three aspects of bacterial translation.Elongation factor G (EF-G) is the target for the antibiotic fusidic acid (FA). LÄS MER

  3. 12. Clostridium difficile : epidemiology and antibiotic resistance

    Författare :Torbjörn Norén; Erik Bäck; Lars G. Burman; Roland Möllby; Örebro universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Clostridium difficile; antibiotic resistance; epidemiology; Medicine; Medicin; Medicin; Medicine;

    Sammanfattning : Clostridium difficile is a spore-forming toxin-producing intestinal bacterium abundant in soils and waters. This pathogen relies on increased growth by a disturbed intestinal microflora and the production of two cytotoxins, toxin A and toxin B, which may cause anything from mild self-limiting C. LÄS MER