Sökning: "fused silica capillaries"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden fused silica capillaries.

  1. 1. Monolithic separation media synthesized in capillaries and their applications for molecularly imprinted networks

    Författare :Julien Courtois; Knut Irgum; Ruth Freitag; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bupivacaine; etching; phosphorylated tyrosine; poly ethylene glycol ; silanization; transmission electron microscopy; fused silica capillaries; isothermal titration calorimetry; local anæsthetic; molecularly imprinted polymer; monolith; nuclear magnetic resonance; Analytical chemistry; Analytisk kemi;

    Sammanfattning : The thesis describes the synthesis of chromatographic media using several different approaches, their characterizations and applications in liquid chromatography. The steps to achieve a separation column for a specific analyte are presented. The main focus of the study was the design of novel molecularly imprinted polymers. LÄS MER

  3. 2. Surface Modified Capillaries in Capillary Electrophoresis Coupled to Mass Spectrometry : Method Development and Exploration of the Potential of Capillary Electrophoresis as a Proteomic Tool

    Författare :Aida Zuberovic; Jonas Bergquist; Ziad El Rassi; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Topology optimization; Design optimization; Material distribution; Wave propagation problems; Inverse problems; Acoustic devices; Medical microwave tomography; High performance computing; Analytical chemistry; Analytisk kemi;

    Sammanfattning : The increased knowledge about the complexity of the physiological processes increases the demand on the analytical techniques employed to explore them. A comprehensive analysis of the entire sample content is today the most common approach to investigate the molecular interplay behind a physiological deviation. LÄS MER

  4. 3. Separation of Proteins with Capillary Electrophoresis in Coated Capillaries with and without Electroosmosis : Studies on Zone Broadening and Analytical Performances

    Författare :Sheila Mohabbati; Douglas Westerlund; Bo Karlberg; Uppsala universitet; []
    Nyckelord :Pharmaceutical chemistry; Capillary electrophoresis; capillary coatings; proteins; zone broadening; zone sharpening; efficiency; resolution; protein-surface adsorption; protein-buffer interaction; analytical performance; Farmaceutisk kemi;

    Sammanfattning : Proteins have such structural features that they may interact with different types of surfaces by all possible forces, i.e., electrostatic, hydrogen bonding, hydrophobic. In this thesis two different types of coatings for fused silica capillaries aimed to eliminate such interactions have been studied. LÄS MER

  5. 4. Fabrication of new silica nano structures and development of new concepts for MALDI-TOF mass spectrometry

    Författare :Andreas Woldegiorgis; Johan Roeraade; Peter J. Schoenmakers; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Chemistry; Kemi;

    Sammanfattning : A technique to alter the morphology of the inner surface of fused silica capillaries has been developed. The internal surface area is enlarged by means of nano-wires of silica, which are grown from the capillary walls. LÄS MER

  7. 5. Development of techniques and methods for drug analysis by packed capillary liquid chromatography with octadecylbonded silica and porous graphitic carbon columns

    Författare :Pernilla Koivisto; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Chemistry; Kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Packed capillary liquid chromatography in combination with ultraviolet and mass spectrometric (MS) detection was explored as an analytical tool for drug analysis. The focus was put on column and sample preparation techniques as well as on fundamental aspects and development of chromatographic separations. LÄS MER