Sökning: "fungal metabolites"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden fungal metabolites.

  1. 1. Drug Metabolites Formed by Cunninghamella Fungi : Mass Spectrometric Characterization and Production for use in Doping Control

    Författare :Axel Rydevik; Mikael Hedeland; Ulf Bondesson; David Cowan; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cunninghamella blakesleeana; Cunninghamella elegans; Doping Control; Drug Metabolites; Glucuronide Production; Mass Spectrometry; Reactive Metabolites; Reference Material; Structural Characterization; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Sammanfattning : This thesis describes the in vitro production of drug metabolites using fungi of the Cunninghamella species. The metabolites were characterized with mainly liquid chromatography-mass spectrometry using ion-trap and quadrupole-time-of-flight instruments. A fungal in vitro model has several advantages e.g. LÄS MER

  3. 2. Volatile metabolites from microorganisms in indoor environments : sampling, analysis and identification

    Författare :Anna-Lena Sunesson; Alvin Fox; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Adsorbents; Analysis; Cultivation; Determination; Gas chromatography; Identification; Indicator substances; Indoor air; Mass spectrometry; Metabolites; Microbial volatile organic compounds; Optimization; Sampling; Sick buildings; Thermal desorption; Aspergillus versicolor; Cladosporium cladosporioides; Paecilomyces variotii; Pénicillium commune; Phialophora fastigiata; Streptomyces albidoflavus;

    Sammanfattning : Microorganisms are able to produce a wide variety of volatile organic compounds. This thesis deals with sampling, analysis and identification of such compounds, produced by microorganisms commonly found in buildings. LÄS MER

  4. 3. Novel biologically active compounds by semisynthesis with fungal metabolites

    Författare :Johan Eriksson Bajtner; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; bioactive compounds.; isovelleral; podoscyphic acid; Natural products; semisynthesis;

    Sammanfattning : Natural products have been shown to be an important source of novel compounds for the development of new drugs and pesticides. However, many biologically active natural products contain reactive functionalities that make them toxic. LÄS MER

  5. 4. Analysis of Secondary Metabolites from Aspergillus fumigatus and Penicillium nalgiovense : Antimicrobial Compounds from Filamentous Fungi Isolated from Extreme Environments

    Författare :Stefan Svahn; Lars Bohlin; Björn Olsen; Ulf Göransson; Erja Chryssanthou; Douglas Kinghorn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aspergillus fumigatus; Penicillium nalgiovense; secondary metabolites; invasive aspergillosis; elicitation; gliotoxin; bis methyl gliotoxin; amphotericin B; Pharmacognosy; Farmakognosi;

    Sammanfattning : This thesis describes the cultivation and extraction of filamentous fungi isolated from extreme environments in the search for new antibiotic compounds. Filamentous fungi are a rich source of medicines including antibiotics, and it is believed that many currently unknown fungal species and bioactive fungal metabolites remain to be discovered. LÄS MER

  7. 5. Terpenoid Conidiation Factors in Penicillium cyclopium

    Författare :Yanhong He; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; acetals; hydrolysis; Biotechnology; Bioteknik; total synthesis; analogues; synthesis; conidiogenone; conidiogenol; terpenoid; Penicillium cyclopium; conidiation inducing activity; Natural product; fungal metabolites;

    Sammanfattning : Filamentous fungi produce asexual dispersive spores (conidia), when conditions are not suitable for apical extension growth. Conidiation (the process by which conidia produced) in genus Penicillium has attracted considerable interest because of its wide usage in different areas. LÄS MER