Sökning: "functional status"

Visar resultat 16 - 20 av 544 avhandlingar innehållade orden functional status.

  1. 16. Death mechanisms compromising hippocampal neurogenesis after status epilepticus

    Författare :Christine Ekdahl Clementson; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; minocycline; lipopolysaccharide; microglia activation; status epilepticus; epilepsy; cysteinyl aspartate-specific proteases; apoptosis; neurogenesis; progenitor cell progeny;

    Sammanfattning : Status epilepticus (SE) leads to neurodegeneration as well as neurogenesis in the adult rat hippocampus. This thesis demonstrates that even if the neurogenic response initially is very pronounced, with a several-fold increase in cell proliferation, the survival of the newly formed neurons is compromised by a death mechanism involving mitochondria-related caspases. LÄS MER

  3. 17. Functional Inference from Orthology and Domain Architecture

    Författare :Mateusz Kaduk; Erik Sonnhammer; Erich Bornberg-Bauer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Orthology; Functional coupling networks; Association networks; Hierarchical groups of orthologs; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Sammanfattning : Proteins are the basic building blocks of all living organisms. They play a central role in determining the structure of living beings and are required for essential chemical reactions. One of the main challenges in bioinformatics is to characterize the function of all proteins. LÄS MER

  4. 18. Aspects on stroke outcome : survival, functional status, depression and sex differences in Riks-Stroke, the National Quality Register for Stroke Care

    Författare :Marie Eriksson; Birgitta Stegmayr; Bo Norrving; Andreas Terént; Bent Indredavik; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; stroke; stroke outcome; registry; sex differences; case fatality; functional recovery; depression; Medicine; Medicin;

    Sammanfattning : Stroke is a major cause of death and disability worldwide. In Sweden, about 30 000 strokes occur each year. The aim of this thesis was to analyse survival, functional outcome and self-reported depression after stroke, and to explore possible differences between men and women in stroke care and outcome. LÄS MER

  5. 19. Immunity & the butterfly : A functional genomic study of natural variation in immunity

    Författare :Naomi L.P. Keehnen; Christopher W. Wheat; Brian Lazzaro; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; eco-immunology; functional genomics; transcriptomics; innate immunity; selection dynamics; melanization; phagocytosis; population genetics; Pieris napi; populationsgenetik; Population Genetics;

    Sammanfattning : Butterflies are ubiquitous and abundant, occurring in a wide variety of environments that contain diverse microbial communities with varied pathogenic pressures. These pathogens and parasites present a constant threat to organisms, and have led to the evolution of complex and intricate immune responses. LÄS MER

  7. 20. Computational Modeling of the Basal Ganglia : Functional Pathways and Reinforcement Learning

    Författare :Pierre Berthet; Anders Lansner; Kenji Doya; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; computational neuroscience; modelisation; reinforcement learning; basal ganglia; dopamine; datalogi; Computer Science;

    Sammanfattning : We perceive the environment via sensor arrays and interact with it through motor outputs. The work of this thesis concerns how the brain selects actions given the information about the perceived state of the world and how it learns and adapts these selections to changes in this environment. LÄS MER