Sökning: "frost"

Visar resultat 6 - 10 av 139 avhandlingar innehållade ordet frost.

  1. 6. Chemotherapy in Childhood Acute Lymphoblastic Leukemia : In vitro cellular drug resistance and pharmacokinetics

    Författare :Britt-Marie Frost; Henrik Schröder; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; cytotoxicity; drug resistance; pharmacokinetics; Acute lymphoblastic leukemia; childhood; in vitro assay; vincristine; doxorubicin; Down`s syndrome; CHS 828.; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

    Sammanfattning : The aims of the studies described in this thesis were to investigate the pharmacokinetics of and cellular resistance to chemotherapy as causes of treatment failure in childhood acute lymphoblastic leukemia (ALL).Leukemic cells from 370 children with newly diagnosed ALL were tested by the Fluorometric Microculture Cytotoxicity Assay to measure their resistance to each of ten standard cytotoxic drugs. LÄS MER

  3. 7. On striatum in silico

    Författare :Johanna Frost Nylén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The basal ganglia are a collection of subcortical nuclei involved in movement and action selection. The striatum is the main input nucleus with extensive projections from the cortex and thalamus, and dopaminergic projections from SNc and VTA. LÄS MER

  4. 8. In vitro characterization of nanodrugs at model lipid membranes

    Författare :Rickard Frost; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; in vitro screening; nanomedicine; drug delivery; drug carrier; supported lipid bilayer; QCM-D; nanoparticle; cell membrane;

    Sammanfattning : The use of nano-sized drug carriers to improve the efficiency of drug delivery has become well established during the past decades. New nanoparticle (NP) formulations for the administration of biopharmaceuticals (e.g. proteins and peptides) emerge at an increasing rate and the need for methods to evaluate their properties is expanding. LÄS MER

  5. 9. Probing the Nano-Bio Interface Using Surface Based Analytical Techniques

    Författare :Rickard Frost; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nanotoxicology; cell membrane; nanomedicine; melanophores; QCM-D; nanomaterial; DPI; AFM; supported lipid bilayer;

    Sammanfattning : In recent years, the use of manufactured nanomaterials has been rapidly increasing in a wide range of application areas. Among others, these areas of application include cosmetics, medicine, clothing, and sporting goods. The small size of nanomaterials offers unique properties that are not possible to obtain by the same material in bulk. LÄS MER

  7. 10. Pretargeting agents and At-211-labeled effector molecules: Synthesis and preclinical evaluation for pretargeted alpha-radioimmunotherapy

    Författare :Sofia Frost; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha particles; astatine-211; avidin; biotin; ovarian cancer; polylysine; pretargeted radioimmunotherapy;

    Sammanfattning : .... LÄS MER