Sökning: "fredrik strand"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden fredrik strand.

  1. 1. Determinants of interval cancer and tumor size among breast cancer screening participants

    Författare :Fredrik Strand; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Breast cancer is the most common cancer of women in Sweden and globally. In the more affluent countries, mammography screening has been in place for a few decades and has successfully reduced mortality. LÄS MER

  3. 2. Breast cancer risk assessment and detection in mammograms with artificial intelligence

    Författare :Yue Liu; Kevin Smith; Hossein Azizpour; Fredrik Strand; Anders Eklund; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mammography; AI; Breast cancer risk; Breast cancer detection; Mammografi; AI; Bröstcancerrisk; Upptäckt av bröstcancer; Datalogi; Computer Science;

    Sammanfattning : Breast cancer, the most common type of cancer among women worldwide, necessitates reliable early detection methods. Although mammography serves as a cost-effective screening technique, its limitations in sensitivity emphasize the need for more advanced detection approaches. LÄS MER

  4. 3. DNA Damage Response of Normal Epidermis in the Clinical Setting of Fractionated Radiotherapy : Evidence of a preserved low-dose hypersensitivity response

    Författare :Fredrik Qvarnström; Ingela Turesson; Gunilla Enblad; Mats Harms-Ringdahl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA damage response; low-dose hypersensitivity; dose response; normal tissue; epidermis; keratinocyte; fractionated radiotherapy; DNA double strand break; DSB; foci; γH2AX; 53BP1; checkpoint; p21; apoptosis; mitosis; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : Investigations of DNA damage response (DDR) mechanisms in normal tissues have implications for both cancer prevention and treatments. The accumulating knowledge about protein function and molecular markers makes it possible to directly trace and interpret cellular DDR in a tissue context. LÄS MER

  5. 4. Antiadhesive agents targeting uropathogenic Escherichia coli : Multivariate studies of protein-protein and protein-carbohydrate interactions

    Författare :Andreas Larsson; Jan Kihlberg; Fredrik Almqvist; Mats Larhed; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Antibacterial; pili; antiadhesive agents; structure based design; statistical molecular design; 2-pyridone; amino acid derivative; galabiose; enaminone; SPR; ELISA; QSAR; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis describes studies directed towards development of novel antiadhesive agents, with particular emphasis on compounds that prevent attachment of bacteria to a host-cell. Three different proteins involved in the assembly or function of adhesive pili in uropathogenic Escherichia coli have been targeted either by rational structure based design or statistical molecular methods. LÄS MER

  7. 5. Adenoviral Control of RNAi/miRNA Pathways in Human Cells

    Författare :Ning Xu; Göran Akusjärvi; Fredrik Söderbom; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; RNAi; miRNA; VA RNA; Virology; Virologi;

    Sammanfattning : RNA interference (RNAi) is a diverse, conserved regulatory mechanism in eukaryotic cells, which silences the target gene expression in a homology-dependent manner. Although it has been well documented that RNAi is an antiviral mechanism in plants and insects, it is still unclear whether RNAi naturally limits viral infections in vertebrates. LÄS MER