Sökning: "forskargrupper"

Visar resultat 1 - 5 av 1828 avhandlingar innehållade ordet forskargrupper.

1. 1. Cerebellar Control of Classical Conditioning

   Författare :Magnus Ivarsson; Neurofysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Associative module; Bilateral; Orbicularis oculi muscle; Inferior olive; Purkinje cell; Eyeblink; Conditioned response; neuropsykologi; neurofysiologi; Neurologi; neurophysiology; neuropsychology; Neurology;

   Sammanfattning : It has previously been shown that the cerebellum is critical for classical conditioning. The experiments presented in this thesis aimed to study how the cerebellum controls conditioned eyeblink responses (CRs) and specifically the efferent path from the cerebellar cortex to the muscles. LÄS MER

3. 2. Hormone-Sensitive Lipase and Protein Kinase B; Molecular characterization in testis, adipose tissue and pancreatic beta cells

   Författare :Lena Stenson; Signaltransduktionsforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; pancreas; beta cells; adipocyte; insulin; Akt; protein kinase B; spermatogenesis; cholesterol esterase; hormone-sensitive lipase; testis; cAMP; Proteins; enzymology; Proteiner; enzymologi;

   Sammanfattning : Hormone-sensitive lipase (HSL) and protein kinase B (PKB) are enzymes that in different ways are associated with lipid metabolism. While HSL is the well-known lipolytic enzyme responsible for hydrolysis of stored triacylglycerols in adipose tissue, PKB is a recently identified serine/threonine protein kinase, ubiquitously expressed and involved in signal transduction pathways induced by insulin and growth factors. LÄS MER

4. 3. Neuronal and glial differentiation of expanded neural stem and progenitor cells; in vitro and after transplantation

   Författare :Cecilia Eriksson Linsmeier; Neurobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gtv-a; RCAS A -EGFP; transplantation; cell detection; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; GFP-actin; glial differentiation; neuronal differentiation; neurospheres; glial cultures; bFGF; EGF; cell expansion; cortical primordium; MGE; LGE; CNS; stem- progenitor cells;

   Sammanfattning : In this thesis we have used cells dissected from the lateral ganglionic eminence (LGE), the medial ganglionic eminence (MGE), and the cortical primordium of the embryonic mouse forebrain. The tissue was dissected from either i) wild-type mice, ii) green fluorescent protein (GFP)-, or iii) Gtv-a-expressing transgenic mice, and subsequently grown and expanded in vitro using two different protocols. LÄS MER

5. 4. Role of platelets and neutrophils in regulating trypsinogen activation and tissue damage in acute pancreatitis

   Författare :Aree Abdulla; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protease activation; adhesion molecule; chemokine; intravital flourecence microscopy; matrix metalloproteinase.;

   Sammanfattning : Acute pancreatitis is an inflammatory disease characterized by a diverse spectrum of clinical presentations ranging from a mild and self-limiting to a severe and systemic disorder. The relationship between inflammation and proteolytic activation in pancreatitis is an elusive issue. LÄS MER

7. 5. Mitochondrial and chromosomal genomics in type 2 diabetes

   Författare :Avinash Abhyankar; Genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adaptive evolution; nuclear-mitochondrial interaction; linkage analysis; QTL; phylogenetic analysis; congenic; type 2 diabetes; GK rat;

   Sammanfattning : Understanding the mechanisms of complex polygenic diseases like type 2 diabetes (T2D) is as complex as their nature. Cellular processes involved in glucose homeostasis need high and reliable energy supply. Mitochondria are the major energy producers in mammalian cells. LÄS MER