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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Towards Improved Diagnostics and Monitoring in Childhood Asthma : Methodological and Clinical Aspects of Exhaled NO and Forced Oscillation Technique

   Författare :Charlotte Heijkenskjöld Rentzhog; Malinovschi Andrei; Lennart Nordvall; Kjell Alving; Lauri Lehtimäki; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; asthma; children; exhaled NO; forced oscillation technique; airway inflammation; small airways; asthma diagnostics; Pediatrik; Pediatrics; Lungmedicin; Lung Medicine;

   Sammanfattning : Background: Asthma is a heterogeneous disease. Diagnosis relies on symptom evaluation and lung function tests using spirometry. Symptoms can be vague. Spirometry is effort-dependent and does not reliably evaluate small airways. LÄS MER

3. 2. Airway mechanics of mice and men

   Författare :Lennart Lundblad; Malmö Klinisk fysiologi och nuklearmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; radiologi; tomografi; tomography; medical instrumentation; Clinical physics; Medicin människa och djur ; Medicine human and vertebrates ; Penh; emphysema; airway resistance; gas conditioning; plethysmography; lung mechanics; Boyle s law; Physiology; medicinsk instrumentering; Klinisk fysiologi; radiology; enhanced pause; pulmonary fibrosis; micro computed tomography; forced oscillation technique; COPD;

   Sammanfattning : In this thesis we explore and further develop several techniques used in the animal laboratory as well as in the clinical setting. In particular, we expand the understanding and usefulness of plethysmographic techniques in small rodents. LÄS MER

4. 3. Lung mechanics and airway inflammation in murine models of asthma

   Författare :Sofia Jonasson; Josephine Hjoberg; Hedenstierna Göran; Carl Persson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; airway inflammation; murine models; lung mechanics; forced oscillation technique; airway reactivity; deep inhalations; oxidative stress; nitric oxide; glucocorticoids.; Clinical physiology; Klinisk fysiologi; klinisk fysiologi; Clinical Physiology;

   Sammanfattning : Allergic asthma is an inflammatory disease of the airways and is characterized by eosinophilic inflammation and increased airway reactivity. In the studies presented in this thesis, lung mechanics and measurements of airway reactivity were assessed in anaesthetized tracheostomized mice by using an animal ventilator (flexiVent®). LÄS MER

5. 4. New methods for optimization of mechanical ventilation

   Författare :Peter Kostic; Peter Frykholm; Anders Larsson; Johan Petersson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mechanical ventilation; optoelectronic plethysmography; forced oscillation technique; laser interferometry; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : Mechanical ventilation saves lives, but it is an intervention fraught with the potential for serious complications. Prevention of these complications has become the focus of research and critical care in the last twenty years. LÄS MER

7. 5. Optimizing mechanical ventilation in extremely preterm infants

   Författare :Linda Wallström; Richard Sindelar; Anders Jonzon; Raffaele Dellaca'; Heikki Lukkarinen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mechanical ventilation; extremely preterm infant; forced oscillation technique; volume targeted ventilation; proportional assist ventilation; phrenic nerve activity; electrical activity of the diaphragm; Pediatrik; Pediatrics;

   Sammanfattning : Extremely low gestational age newborns (ELGANs) i.e. infants born before 28 weeks of gestational age (GA), require respiratory support during their hospital stay, and a majority needs mechanical ventilation (MV) at some time point. LÄS MER