Sökning: "follicular dendritic cells"
Visar resultat 21 - 25 av 25 avhandlingar innehållade orden follicular dendritic cells.
21. Immune mechanisms that determine the quality of antibody responses to vaccines
Sammanfattning : Effective vaccines for many dangerous infectious diseases are still lacking. An improved understanding of the mechanisms that determine the quality of vaccine responses is essential to guide future attempts to design effective vaccines. LÄS MER
22. The role of Ro52 autoantibodies in congenital heart block
Sammanfattning : The presence of B cells producing autoantibodies is a common feature of many autoimmune conditions. The pathogenic role of the autoantibodies is often unclear, but they often serve as diagnostic markers and may be used as prognostic tools in some diseases. LÄS MER
23. Innate immune responses in vivo after antigen administration : implications for vaccine development
Sammanfattning : Inducing high magnitude of antibodies with epitope breadth over prolonged periods of time is likely a prerequisite to prevent several of the world’s most serious infectious diseases such as HIV-1, malaria and tuberculosis for which there are no vaccines yet. A much better understanding of the innate immune mechanisms that are critical for inducing strong responses to vaccination is therefore essential. LÄS MER
24. Advances in exosome-mediated immunotherapy and diagnostics
Sammanfattning : Exosomes are small vesicles with immune-stimulatory capacity, which can activate T cell responses in a B cell dependent manner, and therefore may serve as immune therapeutic tools. Peptide-loaded dendritic cell (DC)-derived exosomes are proven safe in clinical trials, although with limited ability to induce cytotoxic T lymphocyte (CTL) responses or prolong patient survival. LÄS MER
25. Analysis of extracellular vesicles and their application in immunotherapy
Sammanfattning : Extracellular Vesicles (EVs) are nano-sized particles secreted by most, if not all, cell types. They are important mediators in intercellular communication and carry a broad array of biomolecules such as lipids, nucleic acids and proteins. LÄS MER