Sökning: "follicular dendritic cells"

Visar resultat 11 - 15 av 25 avhandlingar innehållade orden follicular dendritic cells.

1. 11. Germinal centers : why and why not? The humoral response in primary immunodeficiency

   Författare :Carin Dahlberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : An efficient and regulated immune system is required for protection against pathogens. B cells are required for a humoral response. For a sustained humoral response against pathogens germinal center (GC) reactions are required. In the GC reaction, B cells with antigen-specific B cell receptors are selected and expanded. LÄS MER

3. 12. Cellular and Molecular Aspects of the Germinal Centre Reaction

   Författare :Katarina Dahlenborg; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; Biotechnology; Bioteknik; transplantation; Immunologi; serologi;

   Sammanfattning : The humoral immune response to a T cell dependent protein antigen will over time generate antibodies with an increased affinity to the antigen. This is due to a process known as affinity maturation and proceeds in a, for this purpose, well designed micro-milieu within secondary lymphoid organs known as germinal centres. LÄS MER

4. 13. The Germinal Centre reaction - Genetic and proteomic analysis of factors important for survival and growth of B lymphocytes

   Författare :Linda Zander; Göteborgs universitet; []
   Nyckelord :B lymphocyte; germinal centre; transformation; serum-free; MHC class II; bare lymphocyte syndrome; extracellular proteins; DNA repair; Polymerase ?;

   Sammanfattning : During an immune response the B lymphocytes main function is to produce antibodies in the specific defence against the pathogen. When naïve B lymphocytes become activated by binding of an antigen, the cells differentiate to become antibody producing plasma cells. LÄS MER

5. 14. The impact of the cytoskeleton dynamics on immune responses

   Författare :Marisa A P Baptista; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Immune cells are susceptible to a variety of external stimuli that triggers cell surface receptors, leading to activation of intracellular proteins and changes in the actin cytoskeleton. The Rho-GTPases are a family of proteins that regulate several aspects of actin polymerization. LÄS MER

7. 15. Soluble intercellular and vascular cell adhesion molecules-1 in lymphoid neoplasms : A clinical and prognostic study of Hodgkin's disease, non-Hodgkin's lymphomas and chronic B-lymphocytic leukaemia

   Författare :Ilse Christiansen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Hodgkin s disease; non-Hodgkin s lymphomas; chronic lymphocytic leukaemia; sICAM-1; sVCAM-1; prognostic markers; VCAM-1; ICAM-1; Hodgkin cell lines; Onkologi; Oncology; Onkologi; Clinical Immunology; klinisk immunologi;

   Sammanfattning : The interaction of soluble adhesion molecules with adhesion ligands expressed by immunological cells interfere with the cell-cell adhesion essential for the signal transductions that initiate immunological responses. Preliminary data suggest that soluble adhesion molecules also promote angiogenesis. LÄS MER