Sökning: "folding complexity"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden folding complexity.

1. 1. The birth and growth of the protein folding nucleus : Studies of protein folding focused on critical contacts, topology and ionic interactions

   Författare :Linda Hedberg; Mikael Oliveberg; Christopher Johnson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein folding; protein stability; two-state folding; chevron plot; transition-state movements; Hammond behaviour; topology; electrostatic interactions; pH dependence; mass-action; protein engineering; pKa; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : Proteins are among the most complex molecules in the cell and they play a major role in life itself. The complexity is not restricted to just structure and function, but also embraces the protein folding reaction. LÄS MER

3. 2. Post-synaptic Density Disc Large Zo-1 (PDZ) Domains : From Folding and Binding to Drug Targeting

   Författare :Celestine Chi; Per Jemth; Maria Selmer; Sarah Linse; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein-protein interaction; protein folding; and drug design; Biochemistry; Biokemi; Biokemi; Biochemistry;

   Sammanfattning : Understanding how proteins fold and bind is interesting since these processes are central to most biological activity. Protein folding and protein-protein interaction are by themselves very complex but using a good and robust system to study them could ease some of the hurdles. LÄS MER

4. 3. On the Size and Shape of Polymers and Polymer Complexes : A Computational and Light Scattering Study

   Författare :Tomas Edvinsson; Terence Cosgrove; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; Monte Carlo simulations; grafted polymers; shape description; folding complexity; clustering; percolation algorithm; light scattering; end-capped polymers; inclusion complexes; Fysik; Physics; Fysik; Physical Chemistry; Fysikalisk kemi;

   Sammanfattning : Detailed characterization of size and shape of polymers, and development of methods to elucidate the mechanisms behind shape transitions are central issues in this thesis. In particular we characterize grafted polymer chains under confinement in terms of the chain entanglement complexity and mean molecular size. LÄS MER

5. 4. Contributions to low-complexity digital filters

   Författare :Oscar Gustafsson; Keshab K. Parhi; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : In this thesis we discuss design and implementation of low-complexity digital filters. Digital filters are key components in many digital signal processing (DSP) systems. Typical applications include interpolation, decimation, and noise suppression.The work presented in the thesis can be divided into four parts. LÄS MER

7. 5. Exact and approximation algorithms for graph problems with some biological applications

   Författare :Eva-Marta Lundell; Data Vetenskap; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Graph algorithms; computational biology; approximation algorithms; computational complexity; evolutionary trees; maximum agreement subtree; graph embedding; shortest cycle; clique partitioning;

   Sammanfattning : In this thesis we study several combinatorial problems in algorithmic graph theory and computational biology, and different algorithmical approaches for solving them. In particular, we focus on graph algorithms, seeking for the most part polynomial or sub-exponential exact solutions, but in some cases also approximate solutions. LÄS MER