Sökning: "focal"

Visar resultat 1 - 5 av 511 avhandlingar innehållade ordet focal.

1. 1. Focal atrial tachycardia : Insights concerning the arrhythmogenic substrate based on analysis of intracardiac electrograms and inflammatory markers

   Författare :Ioan Liuba; Gerhard Hindricks; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Background: Focal atrial tachycardias are tachycardias characterized by a radial spread of activation from a discrete area of the atrial myocardium. They account for 10-15% of supraventricular tachycardias and are generally poorly responsive to pharmacological treatment. The pathophysiologic substrate of these arrhythmias remains poorly understood. LÄS MER

3. 2. Astrocyte metabolism following focal cerebral ischemia

   Författare :Anna E Thoren; Göteborgs universitet; []
   Nyckelord :Astrocyte; metabolism; focal cerebral ischemia; reperfusion; infarct; [1-14C]acetate; [U-14C]glucose; glutamine; glutamate; ATP; ADP; lactate; MCT4; immunogold cytochemistry;

   Sammanfattning : Stroke is one of the leading causes of disability and death. Most often, stroke results from blockage of an artery in the brain leading to tissue infarction within the perfusion territory of the affected vessel. LÄS MER

4. 3. Hyperglycemia and Focal Brain Ischemia : Clinical and Experimental Studies

   Författare :Nasim Farrokhnia; Andreas Terént; Fredrik Lennmyr; Elisabeth Björk; Henrik Hagberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; cerebrovascular disorders; diabetes mellitus; hyperglycemia; infarction; middle cerebral artery; ischemia; mitogen-activated protein kinases; mortality; rats; reactive oxygen species; reperfusion; signal transduction; therapeutics; Invärtesmedicin; Internal medicine; Invärtesmedicin;

   Sammanfattning : Diabetes is a major risk factor for ischemic stroke and is associated with increased mortality. Additionally, hyperglycemia, a common complication in acute stroke, is associated with poor outcome. LÄS MER

5. 4. Signal Transduction in Focal Cerebral Ischemia : Experimental Studies on VEGF, MAPK and Src family kinases

   Författare :Fredrik Lennmyr; Andreas Terént; Tommy Olsson; Uppsala universitet; []
   Nyckelord :Medical sciences; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicin; Medicine;

   Sammanfattning : Cerebral ischemia elicits a wide range of events, including complex activation of various intracellular signaling pathways. This study aims to investigate the expression of vascular endothelial growth factor (VEGF) and the activation pattern of mitogen-activated protein kinases (MAPK) in reponse to focal cerebral ischemia. LÄS MER

7. 5. 11C Molecular Imaging in Focal Epilepsy

   Författare :Torsten Danfors; Eva Kumlien; Jens Sörensen; Elisabeth Ronne-Engström; Juha Rinne; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; positron emission tomography; methionine; NK1; substance p; flumazenil; deprenyl; pk11195; phosphoimager; autoradiography; TBI; traumatic brain injury; iron chloride; ferrous chloride; Neurology; Neurologi; Radiology; Radiologi;

   Sammanfattning : Epilepsy is a common neurological disease affecting 6 million people in Europe. Early prevention and accurate diagnosis and treatment are of importance to obtain seizure freedom. In this thesis new applications of carbon-11-labelled tracers in PET and autoradiographic studies were explored in focal epilepsy. LÄS MER