Sökning: "foam cell formation"

Visar resultat 16 - 20 av 28 avhandlingar innehållade orden foam cell formation.

  1. 16. LDL oxidation, iron, lysosomes, and macrophages in early atherosclerosis

    Författare :Xi Ming Yuan; W. John Eaton; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Oxidation of low density lipoprotein (LDL) may result in its uptake by macrophages with ensuing foam cell formation. Thus, oxidised LDL (oxLDL) may play an important role in atherogenesis. Extensive in vitro evidence is in favour of the notion that LDL oxidation by cells present in atherosclerotic plaques requires the presence of transition metals. LÄS MER

  3. 17. Oxidative stress, macrophages, iron, and atherosclerosis

    Författare :Wei Li; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Macrophages have a great capacity to take up exogenous material, such as oxidatively modified low density lipoproteins (oxLDL) and different sources of iron containing structures. OxLDL is taken up into macrophage lysosomes by receptor-mediated endocytosis, but poorly degraded, resulting in foam-cell formation. LÄS MER

  4. 18. Oxidized Lipids and Lysosomal Pathology in Atherogenesis

    Författare :Wei Li; Wendy Jessup; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Macrophages take up large amount of exogenous materials such as oxidatively modified low-density lipoproteins (oxLDL) and lysosomotropic agents. OxLDL is taken up into macrophage lysosomes through receptor-mediated endocytosis, but poorly degraded, resulting in foam cell formation. LÄS MER

  5. 19. CXCL16 and CD137 in atherosclerosis

    Författare :Dick Wågsäter; Allan Sirsjö; Ewa Ehrenborg; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; atherosclerosis; chemokine; cytokine; endothelial cells; inflammation; low-density lipoprotein; macrophages; scavenger receptor; smooth muscle cells; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Sammanfattning : Atherosclerosis is a progressive inflammatory disease that is characterized by the accumulation of lipids, infiltrated cells and fibrous elements in large arteries. This thesis focuses on the molecular mechanisms behind foam cell formation and inflammation, two central processes in the development of atherosclerosis. LÄS MER

  7. 20. Porous Materials from Cellulose Nanofibrils

    Författare :Nicholas Tchang Cervin; Lars Wågberg; Björn Lindman; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Poröst material; cellulosa nanofibriller; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : In the first part of this work a novel type of low-density, sponge-like material for the separation of mixtures of oil and water has been prepared by vapour deposition of hydrophobic tri-chloro-silanes on ultra-porous cellulose nanofibril (CNF) aerogels. To achieve this, a highly porous (>99%) robust CNF aerogel with high structural flexibility is first formed by freeze-drying an aqueous suspension of the CNFs. LÄS MER