Sökning: "fluorescence in-situ hybridization"
Visar resultat 1 - 5 av 54 avhandlingar innehållade orden fluorescence in-situ hybridization.
1. Telomere analysis of normal and neoplastic hematopoietic cells : studies focusing on fluorescence in situ hybridization and flow cytometry
Sammanfattning : The telomeres are specialized structures at the end of the chromosomes composed of the repeated DNA sequence (TTAGGG)n and specific proteins bound to the DNA. The telomeres protect the chromosomes from degradation and end to end fusions. LÄS MER
Sammanfattning : Fluorescence in situ hybridization (FISH) has been shown to be a valuable andimportant technique in cytogenetics, as a complement to traditional bandinganalysis. This thesis focus on the characterization of chromosomalrearrangements in two hematological neoplasias, myelodysplastic syndrome(MDS) and non-Hodgkin lymphoma (NHL) using FISH. LÄS MER
Sammanfattning : In the field of cancer research and diagnostics it is crucial to have reliable methods for detecting molecules involved in the disease. New and better methods for diagnostics, prognostics and drug delivery therefore remain a permanent aim. LÄS MER
Sammanfattning : Novel techniques are needed to investigate the genetic variation revealed in the first draft of the human genome sequence. Padlock probes are recently developed reagents, suitable for detecting single-nucleotide variations of DNA and RNA in situ or in solution. LÄS MER
Sammanfattning : Widespread presence of toxic and persistent pollutants in the environment, even at low concentrations, causes risks of adverse effects to human health and the ecosystem. Biological methods for treatment of water streams and removal of persistent pollutants are of great interest due to their simplicity, low cost, and mild operational conditions without harmful by-products. LÄS MER