Sökning: "fluorescence in situ hybridization"

Visar resultat 16 - 20 av 57 avhandlingar innehållade orden fluorescence in situ hybridization.

  1. 16. Hypothalamic neuronal circuits involved in the regulation of food intake and body weight : histochemical studies in lean rats and obese mutant mice

    Författare :Matilda Bäckberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :AGRP; arcuate nucleus; BBB; CART; GABA; GABA receptors; immunohistochemistry; in situ hybridization; hypothalamus; LHA; leptin; MCH; NPY; orexin; POMC; tubby;

    Sammanfattning : Obesity is a major health problem because of its dramatic increase in prevalence and its association with type 2 diabetes, coronary heart diseases, hypertension and stroke. It is well known that signals generated in response to feeding behavior are integrated in the brain. LÄS MER

  3. 17. Production of polyhydroxyalkanoates in biological treatment of industrial wastewaters

    Författare :Simon Bengtsson; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; polyhydroxyalkanoates; mixed cultures; glycogen accumulating organisms GAO ; feast and famine; acidogenic fermentation; activated sludge;

    Sammanfattning : In search of more environmentally friendly polymer materials, polyhydroxyalkanoates (PHAs) have been considered as promising candidates. PHAs exhibit a broad range of material properties, can be produced from renewable resources and are completely biodegradable. LÄS MER

  4. 18. Predictive and prognostic biomarkers in oral tongue squamous cell carcinoma

    Författare :Michael Ryott; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Oral tongue squamous cell carcinoma (OTSCC) is an aggressive disease frequently associated with poor prognosis due to the high risk of regional failure and mortality rates have been practically unchanged in Sweden the last fifty years, despite advancements in both diagnostics and treatment. Today we lack means to assess the biological aggressiveness of each individual tumor which varies largely. LÄS MER

  5. 19. Identification and Characterization of Stem Cells in Preleukemia and Leukemia

    Författare :Lars Nilsson; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; extracellulära vätskor; Hematologi; Philadelphia chromosome; acute lymphoblastic leukemia; polycytemia vera; 5q- syndrome; myelodysplastic syndromes; self-renewal; preleukemia; Hematopoietic stem cells; leukemic stem cells; extracellular fluids;

    Sammanfattning : Hematopoietic stem cells (HSCs) are responsible for the daily and life long production of large numbers of mature blood cells through highly regulated self-renewal and multilineage capabilities. Leukemias on the other hand, are characterized by a clonal, dysregulated, lineage skewed proliferation and impaired differentiation as the result of multiple accumulated genetic events. LÄS MER

  7. 20. Biliary strictures in primary sclerosing cholangitis : aspects on inflammation and malignancy

    Författare :Erik von Seth; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Primary sclerosing cholangitis (PSC) is a rare liver disease that is characterized by chronic inflammation of bile ducts with development of fibrosis and strictures. The pathogenic mechanisms involved in this disease are insufficiently understood. LÄS MER