Sökning: "flow immunoassay"
Visar resultat 1 - 5 av 23 avhandlingar innehållade orden flow immunoassay.
1. Sampling, sample treatment, assay and real time monitoring of biotechnological processes using an integrated flow-injection system
Sammanfattning : Microorganisms can be used for production of pharmaceutical substances. With the introduction of gene technology, it is possible to transfer information from one organism to the other, thereby making the receiving organism capable of producing substances that it did not so before. This development is very important for e.g. LÄS MER
2. Enzyme Immunoassay in Combination with Liquid Chromatography for Sensitive and Selective Determination of Drugs in Biosamples
Sammanfattning : Two different sensitive microtitre-plate based enzyme immunoassays were developed and evaluated for determination of the model drug compound, budesonide, in blood plasma. In the first approach, high sensitivity was obtained by using amperometric detection in a flow injection system for determination of the enzyme product p-aminophenol. LÄS MER
3. Membrane-Assisted Isoform ImmunoAssay : Separation and determination of protein isoforms
Sammanfattning : Proteins exist in a variety of isoforms with minor differences, mostly due to their glycosylation patterns, which can modulate their biological functions. It seems to be of clinical relevance to measure the isoform-distribution.Thesis describes a novel technology named Membrane-Assisted Isoform ImmunoAssay (MAIIA). LÄS MER
4. Development and Application of Enzyme- and Antibody-based Assays with Emphasis on Selectivity, Sensitivity and Stability
Sammanfattning : This thesis presents the development, optimisation, and various applications of enzyme-based biosensors and immunoassays, mainly with relevance to environmental analysis. the thesis discusses problems and possible solutions associated with selectivity, sensitivity and robustness of such bioassays with emphasis on various immunoasssay configurations for determination of surfactants, phenols, or drugs, and amperometric biosensors based on enzymes (e. LÄS MER
5. Sample Handling Techniques in Biological and Environmental Applications Emphasizing Biomolecular Recognition and MALDI-TOF MS
Sammanfattning : The use of restricted access media and other stationary phases for clean-up and trace enrichment of environmental samples coupled on-line to liquid chromatography using diode array detection as well as thermospray MS is described. This on-line configuration was compared with commercially available ELISAs for the determination of triazines in complex matrices, showing superior precision and accuracy with the chromatographic method. LÄS MER