Sökning: "flk-1"
Visar resultat 6 - 9 av 9 avhandlingar innehållade ordet flk-1.
6. Trophic factors, neuroprotection and spinal cord repair
Sammanfattning : Background: There is no cure for paralysis. The only drug therapy presently in use, acute high-dose methylprednisolone, has only modest effects on outcome. There is therefore a great need for new therapies. LÄS MER
7. RP59 : a novel stem cell protein and mapping of its expression
Sammanfattning : The purpose of this thesis was to study the expression pattern of a novel protein daring developmental processes. Firstly we identified so far unknown mRNA sequences coding for frequently expressed proteins in primitive mesenchymal cells in bone marrow and osteoblasts. LÄS MER
8. On the role of notch, numb and numblike in development and cancer
Sammanfattning : The development of mutlicellualr organisms relies on a highly conserved signaling network, of which one of the key components is the Notch signaling pathway. The core Notch signaling pathway consists of receptors, ligands and an intracellular mediator. LÄS MER
9. The role of VEGF family in angiogenesis, tumor growth and metastasis
Sammanfattning : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. LÄS MER