Sökning: "five-year outcome"

Visar resultat 16 - 20 av 72 avhandlingar innehållade orden five-year outcome.

  1. 16. Locally recurrent rectal cancer : aspects on management, surgery and outcome

    Författare :Karin Westberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Locally recurrent rectal cancer (LRRC) is a severe condition associated with a high morbidity and mortality, affecting about 150-200 people/year in Sweden. After improvements in management and treatment of primary rectal cancer (RC), including an amelioration and standardisation of surgical technique, improved preoperative staging, addition of preoperative radiotherapy (RT), implementation of multidisciplinary team conferences and postoperative surveillance programmes, the rate of LRRC has decreased dramatically from 30-40% to 5-15%. LÄS MER

  2. 17. Long-term Morbidity and Socioeconomic Outcome among Nordic Childhood Cancer Survivors

    Författare :Anna Sällfors-Holmqvist; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood cancer survivors; late complications; morbidity; late socioeconomic effects;

    Sammanfattning : Survival after childhood cancer has improved dramatically during the past four decades, resulting in a five-year survival rate of 80% in children recently treated for cancer in the Nordic countries. However, these advances in treatment and survival has come at a price, and many survivors face significant treatment-induced sequelae, most of which only become clinically apparent many years after the child has been cured. LÄS MER

  3. 18. Urinary Bladder Carcinoma – Studies of Outcome of Current Management and Experimental Therapy

    Författare :Truls Gårdmark; Per-Uno Malmström; Jörgen Carlsson; Sverker Hellsten; Willem Oosterlinck; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Bladder; Epidemiology; Administration; Intravesical; Radiotherapy; Kirurgi; Surgery; Kirurgi;

    Sammanfattning : The thesis concerns the epidemiology, current and possible future treatment of urothelial cancer of the urinary bladder. The Swedish National Quality Registry for Bladder Cancer 1997-2001 was used to explore epidemiology, current therapies and outcome. More common in men, the incidence for Ta and T1 tumours peaks in the age range 70-79 years. LÄS MER

  4. 19. Obstructive sleep apnea syndrome. Treatment outcome, psychiatric aspects, neuropsychology and quality of life

    Författare :Pia Dahlöf; Göteborgs universitet; []
    Nyckelord :obstructive sleep apnea syndrome; uvulopalatopharyngoplasty; oxygen desaturation index; psychiatric morbidity; depression; dexamethasone suppression test; verbal learning and recall; executive functions; quality of life; spouses; long-term follow-up;

    Sammanfattning : Background: Obstructive sleep apnea syndrome (OSAS) is characterized by snoring and apneas during sleep leading to oxygen desaturation, sleep fragmentation and excessive daytime sleepiness. Prior reports have indicated that psychiatric morbidity associated with sleep apnea might be reversed by intervention correcting the sleep related breathing disorder. LÄS MER

  5. 20. Biological therapies : treatment outcome in RA-patients : quality of life, health economy and pharmacotherapy

    Författare :Jenny Riazzoli; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory systemic autoimmune disorder characterized by symmetric inflammation of synovial joints, leading to progressive erosion of cartilage and bone. The impact of the disease is wide, not only resulting in decreased quality of life (QoL), but also a loss of productivity and an increase in healthcare costs The aim of this thesis was to study the impact of treatment with tumour necrosis factor- alpha inhibitors (TNF-inhibitors) on patients with RA in terms of risk for adverse events, impact on work-force ability and the possibility to predict treatment outcome from early patient reported data. LÄS MER