Sökning: "five-year outcome"
Visar resultat 16 - 20 av 72 avhandlingar innehållade orden five-year outcome.
16. Locally recurrent rectal cancer : aspects on management, surgery and outcome
Sammanfattning : Locally recurrent rectal cancer (LRRC) is a severe condition associated with a high morbidity and mortality, affecting about 150-200 people/year in Sweden. After improvements in management and treatment of primary rectal cancer (RC), including an amelioration and standardisation of surgical technique, improved preoperative staging, addition of preoperative radiotherapy (RT), implementation of multidisciplinary team conferences and postoperative surveillance programmes, the rate of LRRC has decreased dramatically from 30-40% to 5-15%. LÄS MER
17. Long-term Morbidity and Socioeconomic Outcome among Nordic Childhood Cancer Survivors
Sammanfattning : Survival after childhood cancer has improved dramatically during the past four decades, resulting in a five-year survival rate of 80% in children recently treated for cancer in the Nordic countries. However, these advances in treatment and survival has come at a price, and many survivors face significant treatment-induced sequelae, most of which only become clinically apparent many years after the child has been cured. LÄS MER
18. Urinary Bladder Carcinoma – Studies of Outcome of Current Management and Experimental Therapy
Sammanfattning : The thesis concerns the epidemiology, current and possible future treatment of urothelial cancer of the urinary bladder. The Swedish National Quality Registry for Bladder Cancer 1997-2001 was used to explore epidemiology, current therapies and outcome. More common in men, the incidence for Ta and T1 tumours peaks in the age range 70-79 years. LÄS MER
19. Obstructive sleep apnea syndrome. Treatment outcome, psychiatric aspects, neuropsychology and quality of life
Sammanfattning : Background: Obstructive sleep apnea syndrome (OSAS) is characterized by snoring and apneas during sleep leading to oxygen desaturation, sleep fragmentation and excessive daytime sleepiness. Prior reports have indicated that psychiatric morbidity associated with sleep apnea might be reversed by intervention correcting the sleep related breathing disorder. LÄS MER
20. Biological therapies : treatment outcome in RA-patients : quality of life, health economy and pharmacotherapy
Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory systemic autoimmune disorder characterized by symmetric inflammation of synovial joints, leading to progressive erosion of cartilage and bone. The impact of the disease is wide, not only resulting in decreased quality of life (QoL), but also a loss of productivity and an increase in healthcare costs The aim of this thesis was to study the impact of treatment with tumour necrosis factor- alpha inhibitors (TNF-inhibitors) on patients with RA in terms of risk for adverse events, impact on work-force ability and the possibility to predict treatment outcome from early patient reported data. LÄS MER