Sökning: "first-trimester tissues"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden first-trimester tissues.

  1. 1. In vitro studies on human first trimester forebrain cells : differentiation and interactions with immunoregulating molecules

    Författare :Alyaa Mohammed Ali Mousa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis has focused on understanding, at the molecular level, growth regulation and differentiation of human first trimester forebrain cells, and the immune signals mediating these processes. Primary cultures were established from human forebrain tissue derived from elective first trimester abortions. LÄS MER

  3. 2. Mapping Transcriptomes in Tissues

    Författare :Ludvig Larsson; Joakim Lundeberg; Stefania Giacomello; Naveed Ishaque; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; spatially resolved transcriptomics; spatial transcriptomics; transcriptomics; data analysis; rumsligt upplöst transkriptomik; rumslig transkriptomik; transkriptomik; dataanalys; Biotechnology; Bioteknologi;

    Sammanfattning : Over the past few decades, the advent of pioneering biotechnological methods has allowed scientists to analyze the molecular components of multicellular organisms with remarkable precision. The field of transcriptomics has witnessed a rapid development of technologies for gene expression profiling of biological samples. LÄS MER

  4. 3. Levonorgestrel emergency contraception : effects on endometrial development and embryo implantation

    Författare :Chun-Xia Meng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Emergency contraception; levonorgestrel; endometrial receptivity markers; embryo implantation; first-trimester tissues;

    Sammanfattning : Background: The dialog between the developing embryo and receptive endometrium is under the control of ovarian steroids and numerous biomolecules, some of which have been suggested as markers of endometrial receptivity. Unintended pregnancies are common. The standard treatment with levonorgestrel (LNG, 1. LÄS MER

  5. 4. Spatiotemporal Profiling of Human Development Using Multiplexed Imaging

    Författare :Sanem Sariyar; Emma Käller Lundberg; Burcu Ayoglu; Gunilla Westergren-Thorsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; human development; organ development; spatial proteomics; single-cell proteomics; proliferation; immune system; mänsklig utveckling; organutveckling; spatial proteomik; single-cell proteomik; proliferation; immunsystem; Biotechnology; Bioteknologi;

    Sammanfattning : Human development is complex and intricate, where the positions of cells, expression of key markers, and cell-cell interactions contribute to the development of various organs from different germ layers and the establishment of the body axis. Therefore, understanding human development within spatial and temporal aspects is crucial. LÄS MER

  7. 5. Steroid metabolism in human reproductive organs

    Författare :Anna Helena Karypidis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Androgens are involved in the development of prostate cancer. Both UGT2B17 and CYP7B1 are involved in the metabolism of androgens and are highly abundant in the prostate. Deletion of the UGT2B17 gene is associated with low or undetectable urinary testosterone levels. LÄS MER