Sökning: "fibroblast growth factor signaling"

Visar resultat 16 - 20 av 41 avhandlingar innehållade orden fibroblast growth factor signaling.

1. 16. The role of VEGF family in angiogenesis, tumor growth and metastasis

   Författare :Xiaojuan Yang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. LÄS MER

3. 17. Specification of Dorsal and Intermediate Telencephalic Character

   Författare :Matthew Marklund; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; telencephalon; forebrain; dorsoventral patterning; WNT; FGF; RA; retinoid-mediated signaling; development; specification; cortex; striatal; intermediate; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Sammanfattning : The telencephalon is the most highly evolved region of the vertebrate central nervous system (CNS). The major structures of the telencephalon - the cortex and basal ganglia – derive from the dorsally positioned pallium and the ventrally positioned subpallium, respectively. LÄS MER

4. 18. Roles of the Shb and Cbl Proteins in Signal Transduction and Blood Vessel Formation

   Författare :Lingge Lu; Michael Welsh; Lars Holgren; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Shb; Cbl; FGF-2; NGF; PDGF; VEGF; VEGFR-2; differentiation; blood vessel formation; PC12 cells; endothelial cells; embryoid bodies; Rap1; CrkII; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

   Sammanfattning : Formation of blood vessels occurs through two processes: vasculogenesis and angiogenesis, which are regulated by various growth factors such as vascular endothelial growth factor, fibroblast growth factor and platelet-derived growth factor. The present study was carried out in order to investigate the roles of the Shb and Cbl proteins in growth factor-mediated signal transduction and blood vessel formation. LÄS MER

5. 19. FROM GENE TO STRUCTURE: Formation of Iduronic Acid in Dermatan Sulfate by Two DS-epimerases

   Författare :Benny Pacheco; Matrixbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : During embryonic development and adult life a wide range of cell behaviors such as differentiation, proliferation and migration are in effect to maintain tissue integrity and function. An integral part of these dynamic processes is the interplay between the cells and their environment, i.e. the extracellular space. LÄS MER

7. 20. Molecular mechanisms of VEGF-mediated angiogenesis and vascular permeability

   Författare :Anna Eriksson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Angiogenesis; VEGF; vascular permeability;

   Sammanfattning : Angiogenesis, sprouting of new capillaries from pre-existing blood vessels, is a tightly regulated multi-step process. One of the key mediators in this process is the Vascular Endothelial Growth Factor (VEGF). Many tumors express high levels of VEGF and pathological angiogenesis is considered a hallmark of malignant tumor growth. LÄS MER