Sökning: "fetal cornea"

Hittade 4 avhandlingar innehållade orden fetal cornea.

  1. 1. Laminins and alpha11 integrin in the human eye : importance in development and disease

    Författare :Berit Byström; Fatima Pedrosa Domellöf; Ulf Stenevi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; basement membranes; extracellular matrix; laminin; integrin; cornea; development; keratoconus; wound healing; remodeling; immunohistochemistry; Ophtalmiatrics; Oftalmiatrik;

    Sammanfattning : The extracellular matrix (ECM) offers a protective shelter for cells and provides signaling paths important for cell to cell communication. ECM consists of basement membranes (BM) and interstitial matrix. BMs provide mechanical support for parenchymal cells, influence cell proliferation, survival, migration and differentiation. LÄS MER

  3. 2. Aniridia-related keratopathy : structural changes, signaling pathways and clinical aspects

    Författare :André Vicente; Fatima Pedrosa Domellöf; Berit Byström; Luis Abegão Pinto; Jing-Xia Liu; Anders Ivarsen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aniridia; aniridia-related keratopathy; PAX6; keratoplasty; fetal cornea; Notch1; Wnt; sonic hedgehog; mTOR; keratocyte; oftalmiatrik; ophthalmology;

    Sammanfattning : Aniridia is a congenital autosomal dominant, bilateral, panocular condition, caused by haploinsufficiency of the Pax6 transcription factor. Aniridia-related keratopathy (ARK) significantly affects vision and quality of life in these patients. LÄS MER

  4. 3. The role of VEGF family in angiogenesis, tumor growth and metastasis

    Författare :Xiaojuan Yang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. LÄS MER

  5. 4. Primary structure, expression and function of laminin [alpha]4

    Författare :Jarkko Kortesmaa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Basement membranes (BMs) are thin extracellular sheet-like structures that compartmentalize tissues. They are found beneath epithelia and endothelia, and surrounding individual cells, such as muscle fibers, neurons and adipocytes. Laminins, type IV collagens, perlecan and nidogens are some of the main components of mature basement membranes. LÄS MER