Sökning: "febrile neutropenia"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden febrile neutropenia.

  1. 1. Pharmacometric Models for Biomarkers, Side Effects and Efficacy in Anticancer Drug Therapy

    Författare :Emma K. Hansson; Lena Friberg; Mats O Karlsson; Charlotte Kloft; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacokinetics; Pharmacodynamics; Oncology; Febrile Neutropenia; GIST; Sunitinib; PHARMACY; FARMACI; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Sammanfattning : New approaches quantifying the effect of treatment are needed in oncology to improve the drug development process and to enable treatment optimization for existing therapies. This thesis focuses on the development of pharmacometric models for biomarkers, side effects and efficacy in order to identify predictors of clinical response in anti-cancer drug therapy. LÄS MER

  3. 2. Etiology and risk factors of febrile neutropenia in children during cancer treatment

    Författare :Martina Wahlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Side effects due to chemotherapy is still a major issue during cancer treatment. Febrile neutropenia and associated microbiological defined infections (MDIs) are dreaded complications, and still a cause of death during pediatric cancer treatment. LÄS MER

  4. 3. Bacteremia in patients with hematological malignancies and neutropenia

    Författare :Carl Aust; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : For hematological cancer patients, the risk of blood stream infection by bacterial pathogens is increased. Studies on pathogen panorama, efficacy of antimicrobial prophylaxis and antimicrobial resistance are important efforts to decrease morbidity, mortality and the risk of delays or reduction of intensity in cancer treatment. LÄS MER

  5. 4. Infections in patients with haematological malignancies

    Författare :Honar Cherif; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Haematological malignancies; febrile neutropenia; bacteraemia; Candida; oral antibiotic; risk stratification; FUO; cefepime; splenectomy; pneumococcal vaccine;

    Sammanfattning : Infectious complications are an important cause of morbidity and mortality in patients with hematological diseases, especially during chemotherapy induced neutropenia. This study was undertaken with the ultimate goal to improve the clinical management of infections in patients with hematological diseases. LÄS MER

  7. 5. Viral infections in immunocompromised patients

    Författare :Lars Öhrmalm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The number of patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) is steadily increasing, and the outcome of this intervention is largely dependent on how well complications in the form of severe infections can be adequately diagnosed and controlled. Adenoviruses (AdV) have emerged as important causes of morbidity and mortality in these patients. LÄS MER