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  1. 1. Ultrasound based shear wave elastography of the liver : a non-invasive method for evaluation of liver disease

    Författare :Marie Byenfeldt; Anders Elvin; Per Fransson; Odd Helge Gilja; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anthropometric measurement; diagnostic imaging; elasticity imaging technique; blood supply; BMI; body position; fatty liver; liver disease; hepatic steatosis; liver fibrosis; liver stiffness; obesity; postural change; pressure; probe; sex characteristic; shear wave elastography; skin-to-liver capsule distance; transducer and ultrasonography; Radiography; radiografi;

    Sammanfattning : Background: Detecting liver disease at an early stage is important, given that early intervention decreases the risk of developing cirrhosis and subsequently hepatocellular cancer (HCC). The non-invasive ultrasound-based shear wave elastography (SWE) has been used clinically for a decade to assess liver stiffness. LÄS MER

  3. 2. Role of Fatty Acid Composition in Non-Alcoholic Fatty Liver Disease: a Dietary Perspective : Results from Interventional and Observational Studies

    Författare :Michael Fridén; Ulf Risérus; Fredrik Rosqvist; Helen Lindqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fatty acids; Diet; Biomarkers; NAFLD; Liver fat; Fibrosis; Cirrhosis; HCC; Nutrition; Nutrition;

    Sammanfattning : The overall aim of this doctoral thesis was to investigate the role of circulating, liver and dietary fatty acids in non-alcoholic fatty liver disease (NAFLD). For circulating and liver fatty acids, special emphasis was given to fatty acids reflecting diet. LÄS MER

  4. 3. Non-Alcoholic Fatty Liver Disease : A clinical and histopathological study

    Författare :Mattias Ekstedt; Stergios Kechagias; Stefan Lindgren; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroenterology; Gastroenterologi;

    Sammanfattning : Fatty liver has previously often been associated with excessive alcohol consumption. During the last two decades, the interest in fatty liver occurring in non-drinkers i.e. non-alcoholic fatty liver disease (NAFLD) has increased dramatically. LÄS MER

  5. 4. Non-Alcoholic Fatty Liver Disease : Aspects on Diagnosis and Long-term Prognosis

    Författare :Patrik Nasr; Stergios Kechagias; Mattias Ekstedt; Peter Lundberg; Einar Stefán Björnsson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease affecting approximately 25% of the global population and is commonly recognized as the hepatic manifestation of the metabolic syndrome. The histological spectrum of NAFLD ranges from isolated steatosis to non-alcoholic steatohepatitis (NASH), with risk of developing fibrosis and subsequent cirrhosis and hepatocellular carcinoma. LÄS MER

  7. 5. Non-Alcoholic Fatty Liver Disease : Insights into Alcohol Consumption, Genetics, and Proteomics

    Författare :Julia Blomdahl; Stergios Kechagias; Mattias Ekstedt; Maja Thiele; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : NAFLD (Non-Alcoholic Fatty Liver Disease) affects approximately a quarter of the global population and is closely linked to type 2 diabetes mellitus and obesity. The disease spectrum ranges from steatosis and steatohepatitis to fibrosis, cirrhosis, and hepatocellular cancer. LÄS MER