Sökning: "fate mapping"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden fate mapping.
1. Molecular and Cellular Control of Palate Development in the Mouse
Sammanfattning : The formation of a definitive secondary palate in mammals is a multistep process that comprises growth, elevation, contact and fusion of the two palatal shelves. Disruption at any step generates cleft palate, a major congenital birth defect. Therefore, it is important to understand the mechanisms governing normal palate development. LÄS MER
2. Keeping up with retinal photoreceptors and horizontal cells : Labelling and mapping of cells in the normal and diseased embryonic chicken retina
Sammanfattning : The childhood eye cancer retinoblastoma originates from the retina and its development is initiated while the foetus is in the uterus. Retinoblastoma has a reported incidence of 1 in 15-18 000 live births, and approximately 90% of all patients are diagnosed before the age of 5. LÄS MER
3. A Comparative Study of Head Development in Mexican Axolotl and Australian Lungfish: Cell Migration, Cell Fate and Morphogenesis
Sammanfattning : The development of the vertebrate head is a complex process involving interactions between a multitude of cell types and tissues. This thesis describes the development of the cranial neural crest and of the visceral arch muscles in the head of two species. LÄS MER
4. DNA fragility in the context of neural stem cell fate : a multi-method integrative exploration of genome dynamics
Sammanfattning : Recent advances in mapping the complex genetic architecture underlying various debilitating brain disorders have enabled identification of several genetic risk variants. However, these risk variants only explain part of the heritability and vulnerability to these disorders in early development. LÄS MER
5. Lineage commitment to a T
Sammanfattning : he hematopoietic development is a highly dynamic but tightly regulated process. The flexibility to produce blood cells through more than one route will allow the blood system to respond rapidly in stress situations such as infections. LÄS MER