Sökning: "farmaceutisk fysikalisk kemi"

Visar resultat 11 - 15 av 19 avhandlingar innehållade orden farmaceutisk fysikalisk kemi.

1. 11. Release and transport of drugs in some complex and interacting systems

   Författare :Hans Sjöberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry; fysikalisk och oorganisk farmaceutisk kemi;

   Sammanfattning : Drug formulations come in many forms, some intended for direct and immediate action and others aiming at a controlled manner of drug delivery. Viewed in a more general way drug transport often involves charged units, it takes place in a medium which in many respects must be considered complex - to some degree even reactive. LÄS MER

3. 12. Studies on structure and mechanism at formation of solid solutions and solid dispersions of hydrophobic drugs in polymers

   Författare :Marie Wulff; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry; fysikalisk och oorganisk farmaceutisk kemi;

   Sammanfattning : The aim of the studies was to investigate the structures formed and mechanisms involved, when a hydrophobic drug is dispersed in a polymer carrier. The effect of different additives, like surfactants and cyclodextrins, was evaluated. The dispersions were prepared by the melting method. LÄS MER

4. 13. Microgels as drug delivery vehicles : loading and release of amphiphilic drugs

   Författare :Yassir Al-Tikriti; Per Hansson; Magnus Bergström; Matthew Libera; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microgel; amphiphilic drug; phase separation; micropipette; Raman microscopy; controlled release; drug delivery; SAXS; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

   Sammanfattning : Polyelectrolyte microgels are used as delivery vehicles for amphiphilic drugs in, e.g., treatments of liver cancer by a method called trans-arterial chemoembolization. LÄS MER

5. 14. Interaction Between Microgels and Oppositely Charged Peptides

   Författare :Helena Bysell; Martin Malmsten; Per Hansson; Walter Richtering; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; binding; cationic peptides; confocal microscopy; deswelling; distribution; electrostatic; homopolypeptides; microgels; peptides; release; swelling; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

   Sammanfattning : Lightly cross-linked polyelectrolyte microgels are materials with interesting properties for a range of applications. For instance, the volume of these particles can be drastically changed in response to pH, ionic strength, temperature, or the concentration of specific ions and metabolites. LÄS MER

7. 15. Interaction Between Antimicrobial Peptides and Phospholipid Membranes : Effects of Peptide Length and Composition

   Författare :Lovisa Ringstad; Martin Malmsten; Per Hansson; Jeremy Ramsden; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adsorption; antibacterial; antimicrobial peptide; bilayer; ellipsometry; electrochemistry; electrostatic interactions; hydrophobicity; liposome; membrane; monolayer; phospholipid; secondary structure; supported bilayer.; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

   Sammanfattning : Due to increasing problems with bacterial resistance development, there is a growing need for identifying new types of antibiotics. Antimicrobial peptides constitute an interesting group of substances for this purpose, since they are believed to act mainly by disrupting the bacterial membrane, which is a fast and non-specific mechanism. LÄS MER