Sökning: "familial breast cancer"
Visar resultat 16 - 20 av 39 avhandlingar innehållade orden familial breast cancer.
16. Risk characterization of familial cancer using the Swedish family-cancer database with a special reference to breast cancer
Sammanfattning : This thesis reports on epidemiological studies on family related cancer in Sweden. The Family-Cancer Database was constructed in 1996 from several national registries. Family relations were available from the Generation register, cancer cases from the Cancer registry and socioeconomic information from Censuses. LÄS MER
17. Investigation of the genetic basis of familial non-BRCA1/2 breast cancer
Sammanfattning : Breast cancer is the most common female malignancy in the Western world and approximately 510% of all breast cancer cases present with some degree of family history. In the mid-nineties genetic linkage analyses successfully identified two breast cancer predisposing genes, BRCA1 and BRCA2. LÄS MER
18. Molecular genetic analysis of human breast cancer
Sammanfattning : Breast cancer accounts for approximately 20% of all female malignancies with hereditary breast cancer being implicated in 5-10% of these cases. Two highly penetrant hereditary breast cancer genes are known; BRCA1 (17q) and BRCA2 (13q), which also confer an increased risk of cancer at other sites. LÄS MER
19. Genetic Alterations in Early Onset Breast Cancer
Sammanfattning : Cancer is in essence a genetic disease, brought about by an accumulation of alterations in genes that encode proteins responsible for the control of cell growth, cell death and the maintenance of genomic integrity. Recent years have seen the unravelling of numerous genes that are targeted in carcinogenesis. LÄS MER
20. Genetic determinants of postmenopausal breast and endometrial cancer
Sammanfattning : Breast cancer is overall the most common cancer in women worldwide and endometrial cancer is the most common gynaecological cancer in the industrialized world. History of a first-degree relative with breast or endometrial cancer has been related to a twofold increase in risk of the respective diseases. LÄS MER