Sökning: "famciclovir"

Hittade 2 avhandlingar innehållade ordet famciclovir.

  1. 1. Prevention and treatment of hepatitis B virus infection

    Författare :Per Sangfelt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Hepatitis B virus; vaccination; treatment; interferon-alpha; larnivudine; famciclovir;

    Sammanfattning : Despite 25 years of effective vaccines and availability of treatment options for 15 years, hepatitis B virus (HBV) infections continue to be a major global health problem. In Sweden, selective screening and vaccination programmes are used in defined high-risk groups such as newborns of chronic HBV carrier mothers and health care workers with risk of blood exposure. LÄS MER

  3. 2. Distribution of antiviral nucleoside analogues into brain and skin

    Författare :Natalia Borg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis was to study physiological and physico-chemical factors influencing the pharmacokinetics and distribution over the blood-brain barrier of antiviral nucleoside analogues in the rat, and to study the distribution to the human skin in vivo of an anti-herpetic nucleoside analogue. Microdialysis was used to sample the free (unbound) extracellular concentration of the nucleoside analogues from the brain tissue, muscle and blood in the rat and from the dermis of healthy human volunteers. LÄS MER