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Visar resultat 1 - 5 av 23 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Source localisation of epileptiform activity in epilepsy of temporal lobe origin

   Författare :Göran Lantz; Klinisk neurofysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; frequency analysis; ictal; singe photon emission computed tomography; volume conduction; extracranial; intracranial; LORETA; dipole; source localisation; epilepsy; mesolimbic; Fast Fourier Transform; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

   Sammanfattning : In patients with drug resistant partial epilepsy, who are under consideration for epilepsy surgery, interictal and ictal EEG recorded with extracranial electrodes plays an important role in the localisation of the seizure onset area. During the past years, methods have been developed, which can be used to estimate the location of the source of epileptiform activity in the brain from extracranial EEG data. LÄS MER

3. 2. The role of duplex scanning in the management of carotid artery disease

   Författare :Karl Logason; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Duplex scanning; Doppler spectral analysis; duplex criteria; Doppler angle of insonation; carotid artery stenosis; carotid endarterectomy; spontaneous cervical artery dissection; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Sammanfattning : Extracranial carotid artery disease, mainly due to atherosclerosis, is a common cause of stroke. The risk for future stroke can be reduced in selected patients by carotid endarterectomy (CEA). Duplex scanning has been increasingly used for diagnosis of carotid artery disease. LÄS MER

4. 3. The Association Between Beta-Blockade and Clinical Outcomes in the Context of Surgical and Traumatic Stress

   Författare :Rebecka Ahl; Shahin Mohseni; Louis Riddez; Göran Wallin; Olle Ljungqvist; Jonathan Tilsed; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Beta-blocker therapy; adrenergic hyperactivity; physiological stress; trauma; depression; colorectal cancer; complications; mortality;

   Sammanfattning : Traumatic injury and major abdominal surgery are areas in general surgery associated with high rates of morbidity and mortality. The overall colorectal cancer surgery mortality rate is around 4%, with that for emergency surgery more than twice as high as for planned. Surgical morbidity varies between 25% and 45%. LÄS MER

5. 4. Exploring novel therapeutic strategies in neuroblastoma

   Författare :Joanna Szydzik; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neuroblastoma; Anaplastic Lymphoma Kinase; Targeted therapy; ATR inhibition;

   Sammanfattning : Neuroblastoma (NB) is the most frequently diagnosed extracranial tumour in children, which arises from transient embryonal tissue of the neural crest that fails to complete terminal differentiation into neurons. Even after completion of successful therapy, high risk neuroblastoma patients typically suffer from post-treatment induced toxicity which impacts on their ability to lead a normal life. LÄS MER

7. 5. Caspase activation in human neuroblastoma cells: mechanisms and spatiotemporal aspects

   Författare :Elena V. Ivanova; Kerstin Iverfeldt; Boris Zhivotovsky; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; apoptosis; caspase; local caspase activation; neurodegeneration; tau-anchored FRET sensors; tAFS; cancer; neuroblastoma; TNF-related apoptosis inducing ligand; TRAIL; protein kinase C; PKC; X-linked inhibitor of apoptosis protein; XIAP; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Apoptosis is one of the modes of programmed cell death, in which several members of the caspase family of proteases play the central role. However, activation of apoptotic caspases does not necessarily lead to cell death. LÄS MER