Sökning: "extracellular toxin delivery"

Hittade 5 avhandlingar innehållade orden extracellular toxin delivery.

  1. 1. Too close for comfort : The role of Contact-Dependent growth Inhibition (CDI) in interbacterial competition and cooperation

    Författare :Marcus Wäneskog; Sanna Koskiniemi; Paul Rainey; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacterial interactions; cell-cell binding; contact-dependent growth inhibition; CDI; CdiB; CdiA; CdiI; outer-membrane receptor; BamA; OmpC; OmpF; extracellular toxin delivery; Toxin-Antitoxin; TA-system; persister cells; stress tolerance; stress response; rpoS; rssB; quorum sensing; multicellular behavior; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : Contact-Dependent growth inhibition (CDI) was discovered in 2005 in the E. coli isolate EC93. Since then our knowledge of CDI systems and their impact on bacterial communities have increased exponentially. LÄS MER

  3. 2. Bacteria and cancer : from toxin delivery to carcinogenesis

    Författare :Riccardo Guidi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epidemiological evidence link certain chronic bacterial infections to a higher risk of cancer development. Induction of an inflammatory circuit and the accumulation of genomic instability are considered mechanisms by which bacteria contribute to malignant transformation. LÄS MER

  4. 3. Mechanisms of Shiga toxin-mediated signaling and toxicity

    Författare :Karl Johansson; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EHEC; Shiga toxin; Microvesicles; Purinergic Receptors;

    Sammanfattning : AbstractShiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli (EHEC). EHEC strains cause gastrointestinal infection and release Stx that can gain access to the circulation. Patients may develop hemolytic uremic syndrome with extensive kidney damage. LÄS MER

  5. 4. Antigen presentation by dendritic cells and immunomodulation by cholera toxin B subunit. Implications for vaccine development

    Författare :Annie George-Chandy; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dendritic cells; cholera toxin B subunit; antigen-presentation;

    Sammanfattning : Antigen presentation by dendritic cells is the first event that takes place upon initiation of an acquired immune response. The inductive events during antigen presentation will essentially govern the orientation and the magnitude of the subsequent immune responses. LÄS MER

  7. 5. Gene and Protein Expression in Human Gliomas

    Författare :Oscar Persson; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumour associated antigen; immunotherapy; glioma; targeted therapy; microarray; proteomics;

    Sammanfattning : The human gliomas are the most common primary brain tumours. They are highly aggressive with a rapid fatal progression for the patient. The invasive growth pattern and inherent resistance to radiation and chemotherapy account for a lack of efficient therapies. LÄS MER