Sökning: "extracellular DNA"

Visar resultat 16 - 20 av 168 avhandlingar innehållade orden extracellular DNA.

  1. 16. Neutrophil extracellular traps in cancer and cancer-associated thrombosis

    Författare :Axel Rosell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer is associated with a hypercoagulable state, and venous thromboembolism (VTE) may be the first sign of occult cancer. Cancer screening of all patients presenting with VTE would, however, overload the healthcare system and burden patients with unnecessary investigations. LÄS MER

  3. 17. On Generation and Function of Neutrophil Extracellular Traps in Abdominal Sepsis

    Författare :Avin Hawez; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal sepsis; inflamation; neutrophil; neutrophil extracellular traps; mRNA; adhesion.;

    Sammanfattning : AbstractSepsis is a clinical condition that develops when the immune system over-response to an infection. Sepsis can lead to organ failure as well as subsequent death. Sepsis-induced host response involves neutrophil over activation which can lead to self tissue damage. LÄS MER

  4. 18. Transcriptional control of Bactericidal/permeability increasing protein (BPI) and cathepsin G in myeloid cells

    Författare :Andreas Lennartsson; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; extracellulära vätskor; Hematologi;

    Sammanfattning : The neutrophil store its effector proteins in several distinct types of cytoplasmic granules, developed sequentially during cell maturation. The different subtypes of granules have unique protein content and functional characteristics. The formation of each granule subtype coincides with the biosynthesis of its content. LÄS MER

  5. 19. Innate immune responses to Mycobacterium tuberculosis infection : How extracellular traps and trained immunity can restrict bacterial growth

    Författare :Clara Braian; Maria Lerm; Olle Stendahl; Parasa Venkata Ramanarao; Nordenfelt Pontus; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis, and the cause of 1.5 million deaths in 2018. During a pulmonary TB infection, the bacterium reaches the lungs and is phagocytosed by cells of the innate immune system, primarily macrophages. LÄS MER

  7. 20. The Wilms' tumor gene 1 (WT1) and leukemia -new insights and further complexity

    Författare :Emelie Svensson; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; cancer; Haematology; extracellular fluids; Hematologi; extracellulära vätskor; Cytologi; cancerology; oncology; Cytology; Medicin människa och djur ; Medicine human and vertebrates ; Cofilin 1; NDRG2; IRF-8; BCR ABL1; hematopoiesis; Wilms´ tumor gene 1; leukemia;

    Sammanfattning : The Wilms tumor gene 1 (WT1) encodes a zinc-finger containing transcription factor which is highly expressed in immature hematopoietic progenitor cells. A high expression of WT1 and the presence of somatic mutations in acute leukemia indicate a role for WT1 in the pathogenesis of leukemia. LÄS MER