Sökning: "experimental colitis"

Visar resultat 11 - 15 av 23 avhandlingar innehållade orden experimental colitis.

  1. 11. Ropivacaine and cellular functions : towards an understanding of efficacy in ulcerative colitis

    Författare :Titti Martinsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Ulcerative colitis is an inflammatory condition affecting the mucosa of the colon and the disease is characterised by periods of active colonic inflammation, intermitted by periods of remission. Local anaesthetics have been shown to exhibit a wide array of anti inflammatory effects in addition to the reversible block of nerve impulse propagation, and some or maybe all of these may explain the reported beneficial effects of local anaesthetics in ulcerative colitis patients. LÄS MER

  3. 12. Characteristics and Consequences of Thymic Involution in Inflammatory Bowel Disease. Experimental studies in G?i2-deficient and DSS-induced Colitis as well as in IBD patients

    Författare :Kristina Elgbratt; Göteborgs universitet; []
    Nyckelord :Inflammatory bowel diseaseInflammatory bowel disease; G?i2- - mice; dextran sodium sulfate; thymocytes; T cell receptor excision circles TRECs ; resent thymic emigrants;

    Sammanfattning : Characteristics and Consequences of Thymic Involution in Inflammatory Bowel Disease. Experimental studies in G?i2-deficient and DSS-induced Colitis as well as in IBD patients Kristina Elgbratt Department of Microbiology and Immunology, Institute of Biomedicine, The Sahlgrenska Academy, G?teborg University, G?teborg Sweden Inflammatory Bowel Disease (IBD) is a chronic relapsing inflammatory disorder of the gastrointestinal tract, comprising ulcerative colitis and Crohn?s disease. LÄS MER

  4. 13. Neuromuscular function in the normal and inflamed colon. An experimental study in rat

    Författare :Lars Börjesson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; dextran sulphate sodium; DMPP; enteric nervous system; McN-A-343; nitric oxide; non-adrenergic; rat; second messenger; smooth muscle; VIP;

    Sammanfattning : Neuromuscular function of the longitudinal muscle layer of distal colon was investigated in segments from normal rats and from rats with colitis induced by dextran sulphate sodium (DSS) at 3% for 3 or 7 days or 5% for 7 days. The study was performed in vitro, on spontaneous tone, or after precontraction. LÄS MER

  5. 14. Effects of Dietary Fibre and Probiotics on Hindgut Fermentation in Healthy Rats and in Rats with Dextran Sulphate Sodium-Induced Colitis and Colon Cancer

    Författare :Camilla Bränning; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carboxylic acids; probiotics; short-chain fatty acids; hindgut fermentation; Colonic health; prebiotics; microbiota; dietary fibre;

    Sammanfattning : The importance of colonic fermentation has been realised during recent years as it has been found to be associated with colonic health and thus the overall health of the individual. The fermentation of dietary fibre and the addition of probiotics can have positive effects on the luminal environment and the colonic microbiota. LÄS MER

  7. 15. The role of nitric oxide in the gastrointestinal tract

    Författare :Linda Gillberg; Per Hellström; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nitric oxide (NO) is an important second messenger involved in the regulation of a multitude of mechanisms in the body, such as neurotransmission, smooth muscle contractility, host defense and immune regulation. Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic disorders affecting the gastrointestinal (GI) tract with unknown etiology. LÄS MER