Sökning: "experimental animal models"

Visar resultat 1 - 5 av 231 avhandlingar innehållade orden experimental animal models.

  1. 1. Assessment of eosinophil degranulation in allergic diseases and experimental models

    Författare :Monika Malm-Erjefält; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood; histochemistry; cytochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur; animal morphology; Animal anatomy; Djurs anatomi och morfologi; Haematology; cytoplasmic granules ; Hematologi; Respiratory system; extracellulära vätskor; Andningsorganen; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Klinisk biologi; Pharmacological sciences; Histology; cell separation ; mice; animal models ; biological marker ; transmission electron microscopy allergy; cell degranulation ; Clinical biology; extracellular fluids; eosinophils;

    Sammanfattning : In allergic disorders, the eosinophilic granulocytes migrate to affected tissues and release granule proteins with cytotoxic, immunoregulatory, and remodeling-promoting properties. Given that degranulation is reflected by a loss in eosinophil granule density of living cells, or by cell membrane rupture and release of intact granules, these morphological changes may represent a biomarker of the allergic disease. LÄS MER

  2. 2. Traumatic brain injury in humans and animal models

    Författare :Elham Rostami; Mårten Risling; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; Experimental models; BDNF; Genetic; Biomarkers; TBI and immunology; Complement; Gene array; Blast TBI; Medical Genetics; Medicinsk genetik; Neuroscience; Neurovetenskap; Neurosurgery; Neurokirurgi; Molecular Immunology; Molekylär immunologi; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : .... LÄS MER

  3. 3. Experimental porcine models of retinal ischemia

    Författare :Håkan Morén; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retinal ischemia; animal model; multifocal electroretinography; intraarterial coiling; retinal vasculature;

    Sammanfattning : Retinal ischaemia resulting from e.g. diabetes, vein thrombosis or arterial occlusion, is one of the major causes of visual impairment and blindness. Although new methods of treatment are being developed, there is still a need for more effective pharmacological forms of treatment. LÄS MER

  4. 4. Surgery and Ischemia in Uterus Transplantation. Studies in various experimental models

    Författare :Caiza Wranning; Göteborgs universitet; []
    Nyckelord :animal models; cold ischemia-reperfusion injury; inflammation; transplantation; uterus;

    Sammanfattning : The use of transplantation to enhance quality of life is a growing clinical field that also includes transplantation of reproductive organs. Transplantation of the uterus has been suggested as future method to treat uterus factor infertility. LÄS MER

  5. 5. Experimental models with specific approaches to augment human fetal liver cell engraftment

    Författare :Pradeep B Patil; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transplantation; Cell therapy; Animal models;

    Sammanfattning : Experimental models with specific approaches to augment human fetal liver cell engraftment Pradeep Patil Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg Background: Liver disease is a common cause of morbidity and mortality worldwide. Orthotopic liver transplantation has so far been the only available therapy for patients with end-stage liver failure. LÄS MER