Sökning: "exercise and brain health"
Visar resultat 1 - 5 av 28 avhandlingar innehållade orden exercise and brain health.
1. Aerobic fitness and healthy brain aging : cognition, brain structure, and dopamine
Sammanfattning : Background: Performing aerobic exercise and maintaining high levels of aerobic fitness may have positive effects on both brain structure and function in older adults. Despite decades of research however, there is still a rather poor understanding of the neurocognitive mechanisms explaining the positive effects of aerobic exercise on cognition. LÄS MER
2. Brain function and glucocorticoids in obesity and type 2 diabetes including effects of lifestyle interventions
Sammanfattning : Background Obesity and associated metabolic dysregulation are linked to impaired cognitive function and alterations in brain structure, which increases the risk of age-related dementia. Increased glucocorticoid (GC) exposure may be a potential mediator of these negative effects on the brain. LÄS MER
3. The role of socio-emotional factors for cognitive health in later life
Sammanfattning : With increasing life expectancies in most parts of the world, the prevalence of dementia and other age-related chronic diseases is growing. Several factors affect future projections and are discussed in this thesis, including possible limits to a continued growth of life expectancy. LÄS MER
4. Effects of PGC1a-induced exercise adaptations in muscle on plasticity and recovery mechanisms in the CNS
Sammanfattning : In this thesis, we sought to determine if muscle-derived exercise-induced signaling via PGC-1α muscle activation influences neuroplasticity under physiological or pathophysiological conditions. For this purpose, transgenic mice with muscle-specific overexpression of PGC-1α that display an endurance exercise muscle phenotype were evaluated in models of cranial irradiation and photothrombotic stroke, as well as in aging and in a voluntary running paradigm. LÄS MER
5. Brain Regeneration - in vitro and in vivo studies of exercise-related effects on brain plasticity
Sammanfattning : Neural stem and progenitor cells in the germinal regions of the adult brain, such as the hippocampus, are of great interest, because they provide the possibility for enhanced brain plasticity or can contribute to endogenous cell replacement after injury or disease. Voluntary exercise was recently shown to robustly induce cellular and structural plasticity, thereby contributing to overall brain health. LÄS MER
