Sökning: "excitability"

Visar resultat 11 - 15 av 77 avhandlingar innehållade ordet excitability.

1. 11. Dissecting the intrastriatal neuronal circuitry that regulates direct and indirect striatal projections

   Författare :Henrike Planert; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :basal ganglia;

   Sammanfattning : The basal ganglia (BG) are a group of subcortical nuclei that are interconnected in multiple parallel cortico-BG-thalamocortical loops. They have been implicated in many functions, among them action control and motor learning. The striatum forms the main input nucleus of the BG. LÄS MER

3. 12. Neural control of standing posture

   Författare :Craig Tokuno; Andrew Cresswell; Alf Thorstensson; Marc Carpenter; Thomas Sinkjær; Gymnastik- och idrottshögskolan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Medicin Teknik; Medicine Technology; Posture; motor cortex; electromyography; kinematics; H-reflex; pre-synaptic inhibition; transcranial magnetic stimulation;

   Sammanfattning : When humans are asked to stand normally, they are not completely motionless. Rather, small amounts of body movement, termed postural sway, can be observed. Although the postural sway of standing has been well described, the manner in which this sway is neurally controlled and its influence in tasks involving postural re-stabilization are not known. LÄS MER

4. 13. Effects pf hypoxia and antiepileptic drugs of electrophysiological properties of CA1 neurons in hippocampus

   Författare :Marita Englund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Antiepileptic drug; brain slice; epilepsy; hippocampus; hypoxia; patchclamp; rat;

   Sammanfattning : This thesis is based on three experimental studies (I-III) of CA1 hippocampal neurons in rat brain slices, where the electrophysiological properties are examined with patch clamp technique under hypoxic conditions and during treatment with antiepileptic drugs, respectively. The cells were visualized and identified in the slice by means of infrared differential interference contrast (IR-DIC) video microscopy and the experiments were carried out at room temperature (22-25 ºC). LÄS MER

5. 14. Movement Behaviors and Cognitive Health for Office Workers

   Författare :Emil Bojsen-Møller; Maria Ekblom; Jonna Nilsson; Carl-Johan Boraxbekk; Teresa Liu-Ambrose; Gymnastik- och idrottshögskolan; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Movement behavior; Physical activity; Sedentary behavior; cognitive functions; neuroplasticity; Medicin Teknik; Medicine Technology;

   Sammanfattning : The lifetime trajectories of movement behavior and cognitive functioning depend on complex interactions between genetic and environmental factors. There is substantial evidence suggesting that physical activity benefits cognitive functions. However, how sedentary behavior and the composition of movement behaviors (i.e. LÄS MER

7. 15. Molecular Mechanisms of Resin Acids and Their Derivatives on the Opening of a Potassium Channel

   Författare :Nina Ottosson; Fredrik Elinder; David Engblom; Bertil Hille; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Voltage-gated ion channels play fundamental roles in excitable cells, such as neurons, where they enable electric signaling. Normally, this signaling is well controlled, but brain damage, alterations in the ionic composition of the extracellular solution, or dysfunctional ion channels can increase the electrical excitability thereby causing epilepsy. LÄS MER