Sökning: "evren alici"

Hittade 2 avhandlingar innehållade orden evren alici.

1. 1. Therapeutic potential of natural killer cells in multiple myeloma

   Författare :Evren Alici; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Natural Killer cells; immunotherapy; multiple myeloma; gene therapy;

   Sammanfattning : Multiple Myeloma (MM) is an incurable plasma cell neoplasm with a median length of survival after diagnosis of approximately three years; therefore new treatment modalities to eradicate the disease are needed. Although the disease remains incurable, current main alternatives are drug treatment modalities and autologous stem cell transplantation (ASCT). LÄS MER

3. 2. CD40L Gene Therapy for Solid Tumors

   Författare :Lina Liljenfeldt; Thomas Tötterman; Angelica Loskog; Sara Mangsbo; Evren Alici; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD40L; adenovirus; tumor immunology; tumor microenvironment; immunotherapy; local immunotherapy; antigen presentation; Immunologi; Immunology;

   Sammanfattning : Adenoviral CD40L gene therapy (AdCD40L) is a strong inducer of anti-tumor immune responses via its activation of dendritic cells (DCs). Activated DCs can in turn activate T cells, which are key players in an efficient anti-tumor response.This thesis includes three papers that focus on different aspects of AdCD40L gene therapy. LÄS MER