Sökning: "evidence based medicine"

Visar resultat 11 - 15 av 557 avhandlingar innehållade orden evidence based medicine.

  1. 11. Epigenetic changes and immunological features of chronic obstructive pulmonary disease

    Författare :Jonas Eriksson Ström; Annelie F. Behndig; Anders Bucht; Anne Lindberg; Erik Melén; Fabbri Leonardo M.; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; immunology; epigenetics; KOLIN; lungmedicin; Lung Medicine; immunologi; Immunology; medicinsk genetik; Medical Genetics;

    Sammanfattning : Background: Chronic obstructive pulmonary disease (COPD) is a heterogenous and chronic inflammatory syndrome with the lungs as its main target organ. Clinically, COPD is characterized by airflow limitation, chronic respiratory symptoms, and many extrapulmonary comorbidities. LÄS MER

  3. 12. Anxiety among Adolescents : Measurement, Clinical Characteristics, and Influences of Parenting and Genetics

    Författare :Susanne Olofsdotter; K.W. Nilsson; Tomas Furmark; Mats Humble; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescent; anxiety; assessment; prevalence; comorbidity; parenting; oxytocin; gene–environment interaction; differential susceptibility; Child and Youth Psychiatry; Barn- och ungdomspsykiatri;

    Sammanfattning : Anxiety is the most commonly reported mental health problem among adolescents. Still, many adolescents in need of treatment are not detected and the clinical characteristics and etiological pathways of adolescent anxiety are under-researched topics. LÄS MER

  4. 13. Aquaporins in Infection and Inflammation

    Författare :Angelika Holm; Elena Vikström; Karl-Eric Magnusson; Vesa Loitto; Jonas Wetterö; Mikael Rhen; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The ability of eukaryotic cells to change their shape and to migrate directionally is highly dependent on active volume regulation in cells building up tissues as well as in individual cells. Transmembrane fluxes of water via specialized water channels, called aquaporins (AQPs), facilitate the changes of volume and shape, which additionally require a complex interplay between the plasma membrane and the cytoskeleton. LÄS MER

  5. 14. Factors affecting the pharmacological treatment of bipolar disorder

    Författare :Louise Öhlund; Ursula Werneke; Michael Ott; Mikael Sandlund; Allan Young; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lithium; Bipolar Disorder; Schizoaffective Disorder; Physical Health; Compliance; Medication Adherence; Side Effects; Long Term Adverse Effects; Mood Stabiliser; Admission; Hospitalisation; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Self-Injurious Behaviour; Non-Suicidal Self Injury; Suicide Attempted; Suicide; psykiatri; Psychiatry;

    Sammanfattning : Background: In patients with bipolar disorder, long-term treatment with mood-stabilisers is often required to prevent manic and depressive episodes. At present, our knowledge remains limited regarding factors that influence the outcomes of mood-stabiliser treatment. LÄS MER

  7. 15. Role of extracellular ATP in immune mechanisms against infections

    Författare :Lalitha Tadala; Andrea Puhar; Sara I Wilson; Bernt Eric Uhlin; Mikael Sellin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular ATP; invasive bacteria; Shigella; Listeria; plasma membrane ruffle; PIEZO1; infection; immune response; Hanta virus; molekylär cellbiologi; molecular cell biology;

    Sammanfattning : Inflammation is driven either by infection with pathogens or sterile stimuli, such as tissue damage or autoimmune diseases. Upon tissue damage, ATP is released passively from the dead or compromised cells. During stress, ATP can be secreted from the cells. Extracellular ATP (eATP) acts as an endogenous danger signal. LÄS MER