Sökning: "estrogen receptor â"
Visar resultat 1 - 5 av 264 avhandlingar innehållade orden estrogen receptor â.
1. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking
Sammanfattning : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. LÄS MER
2. Sex differences in immune response and sex hormone receptor expression in healthy individuals and during viral infection
Sammanfattning : There is sex-bias in morbidity and mortality from infectious diseases. Infections kill more men than women and several studies have pointed out differences in the immune system as a reason. The sex hormones estrogen, progesterone and testosterone all shape the effect of the immune response on multiple levels. LÄS MER
3. Expression and function of vascular estrogen receptors alpha and beta
Sammanfattning : Estrogen receptors (ER) are expressed not only in classical target organs for estrogen like breast and uterus, but also in male reproductive system as well as in non-reproductive organs such as brain, liver and bone. The functions of ER are quite well known in reproductive organs but less information is available regarding their function in vascular tissue. LÄS MER
4. Estrogen and Glucocorticoid Metabolism
Sammanfattning : Background: Cardiovascular disease (CVD) is the leading cause of death among women in Sweden. The risk of CVD increases rapidly after the menopause. A major contributing factor may be the redistribution of adipose tissue, from the peripheral to central depots, associated with menopause. LÄS MER
5. Erythropoietin receptor in growth control and anti-estrogen resistance of estrogen receptor positive breast cancer
Sammanfattning : The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Therefore, recombinant human EPO (rhEPO) is used to treat anemia in cancer patients, but some studies have reported that rhEPO treatment might promote tumor progression. Additionally, EPOR expression has been detected in various cancer forms. LÄS MER