Sökning: "esophagus squamous cell carcinoma"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden esophagus squamous cell carcinoma.

1. 1. Biological Functions of Iduronic Acid in Chondroitin/Dermatan Sulfate in Tumor and Brain Development

   Författare :Martin Thelin; Matrixbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; iduronic acid; chondroitin sulfate; esophagus squamous cell carcinoma; cancer; MET receptor; dermatan sulfate; hepatocyte growth factor; DS-epimerase 2; DS-epimerase 1;

   Sammanfattning : Cell behavior such as migration and proliferation, especially during cancer development, are balanced by the surrounding environment. Complex polysaccharides called glycosaminoglycans (GAGs) are part of this environment and they are known to modulate tumor development. LÄS MER

3. 2. Risk factors for esophageal squamous cell carcinoma

   Författare :Dariush Nasrollahzadeh Nesheli; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :esophageal cancer;

   Sammanfattning : Aims: The etiology of esophageal squamous cell carcinoma (ESCC) in the high risk areas is largely unknown and a few environmental risk factors which have been identified do not explain its oddly high incidence in esophageal cancer belt. The aims of this thesis were to investigate the association of opium/tobacco consumption, serologic gastric atrophy, gastric mucosa-associated microbiota and contact with farm animals with the risk of ESCC. LÄS MER

4. 3. Cancer of the esophagus and gastric cardia : etiological aspects

   Författare :Jesper Lagergren; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Esophageal; gastric cardia; cancer; adenocarcinoma; squamous cell carcinoma; gastroesophageal reflux; body mass; weight; energy intake; physical activity; tobacco; snuff; alcohol; human papillomavirus; sex hormones;

   Sammanfattning : Esophageal cancer is one of the most lethal forms of cancer and the prognosis has not improved substantially during recent decades despite new treatments and diagnostic methods. In view of these discouraging results it is important to identify risk factors that might make primary prevention possible. LÄS MER

5. 4. Role of the CDKN2A and related cell cycle regulatory genes in melanoma and other human cancers

   Författare :Johanna Smeds; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :CDKN2A; ARF; p53; cell cycle regulation; mutation; melanoma; esophageal squamous cell carcinoma;

   Sammanfattning : The main objective of this thesis has been to investigate the involvement of the CDKN2A (p16INK4a and p14ARF) and related cell cycle regulatory genes in melanoma and other types of human cancer. The CDKN2A gene represents a unique locus in the entire human genome. LÄS MER

7. 5. Nuclear medicine imaging of lung cancer and esophagus cancer

   Författare :Gunnar Herlin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Lung cancer;

   Sammanfattning : Background: Somatostatin receptors (SSTRs) occur in cancer tissue, and 99mTc-depreotide is a labelled somatostatin receptor analogue, binding to SSTRs subtype 2, 3, and 5. Purpose: The general aim of the present thesis was to study somatostatin receptor scintigraphy (SSTRS) with 99mTc-depreotide in the diagnosis and characterization of cancers in the lung and oesophagus. LÄS MER