Sökning: "epithelium"

Visar resultat 21 - 25 av 495 avhandlingar innehållade ordet epithelium.

  1. 21. Citrobacter rodentium and Escherichia coli interactions with mucus producing colonic epithelical cells

    Författare :Sinan Sharba; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; A E pathogens; cytokines; epithelium; mitochondria; mucus;

    Sammanfattning : The epithelial cells together with the mucus layer protect the host from noxious luminal substances and pathogenic invasion. Pathogens have evolved numerous strategies to circumvent these barriers and mount infection. C. rodentium is a murine model for the attaching and effacing intestinal E. LÄS MER

  3. 22. Regulation of spontaneous tone in guinea pig trachea

    Författare :Staffan Skogvall; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tetrodotoxin; lidocaine; substance P; tachykinin; prostaglandin; indomethacin; capsaicin; neuroepithelial endocrine cells; epithelium; oxygen; oscillations; spontaneous tone; Asthma; airway smooth muscle; electrical field stimulation.; Physiology; Fysiologi;

    Sammanfattning : Asthma is a common disease, characterized by periods of bronchoconstriction of unclear origin. This thesis examines a specific behavior of airway smooth muscle, the so-called spontaneous airway tone. It was suspected that a defect regulation of this tone may be a cause of asthmatic bronchoconstriction. LÄS MER

  4. 23. Intestinal Ischemia and Reperfusion Injury - Pathophysiology as basis for novel treatment

    Författare :Zhengwu Sun; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; organ dysfunction; epithelium; endothelium; adhesion molecules; cytokines; protease inhibitor; Intestine; barrier; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Intestinal ischemia and reperfusion (I/R) is not infrequent in the clinical situation and the intestinal barrier plays an important role in gut barrier function, preventing not at least septic complications and potentially the development of the multiple organ dysfunction syndrome. Mechanisms of intestinal I/R induced gut epithelial and endothelial barrier dysfunction and remote organ dysfunction, as well as potential preventive and therapeutic modes of management were evaluated in the rat. LÄS MER

  5. 24. Aldehyde toxicity in human oral epithelium

    Författare :Jan Anders Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Oral epithelium; cell cultures; toxicity; transformation; aldehydes; thiols; ADH3;

    Sammanfattning : Human oral epithelium is an established target for aldehyde toxicity, including from usage of tobacco, intake of foods and fluids, leaching of dental materials, and from mouth inhalation of aldehydes in the work environment. Following establishment of culture/exposure protocols for oral cell cultures, toxicity mechanisms and risk of malignant transformation from aldehyde exposure was investigated, including the metabolic defense offered by alcohol dehydrogenase 3 (ADH3) against formaldehyde toxicity. LÄS MER

  7. 25. Tight juntion in ovarian surface epithelium and epithelial ovarian tumors

    Författare :Yihong Zhu; Göteborgs universitet; []
    Nyckelord :junction; claudin; ovarian surface epithelium; epithelial ovarian tumor; TGF-?1;

    Sammanfattning : Epithelial ovarian cancer originating from ovarian surface epithelium (OSE) is the most lethal type of gynecological cancer among women worldwide. The poor understanding of the cellular and molecular events associated with ovarian carcinogenesis leads to difficulties in early diagnosis and in efficient treatment. LÄS MER