Sökning: "epithelial sodium channel ENaC"
Hittade 5 avhandlingar innehållade orden epithelial sodium channel ENaC.
1. Clinical and genetical studies in cystic fibrosis and pseudohypoaldosteronism
Sammanfattning : Cystic fibrosis (CF) is the most common severe autosomal recessive disorder among Caucasians and is caused by mutations of the chloride channel, CFTR (cystic fibrosis transmembrane conductance regulator) gene. Despite a markedly improved median survival many CF patients still die at a young age. LÄS MER
2. Genetic factors in primary hypertension- with emphasis on renal sodium reabsorption
Sammanfattning : Genetic factors are of importance for the development of primary hypertension (HT). Intrauterine growth retardation, salt sensitivity and insulin resistance are all characteristic features of individuals prone to develop HT. LÄS MER
3. Development and regulation of alveolar fluid clearance in the guinea pig
Sammanfattning : Alveolar fluid clearance is driven by active absorption of Na+ across the alveolar epithelium. Development and hormonal regulation of alveolar fluid clearance over 1 hour was studied by instillation of a protein-containing, isosmolar fluid into lungs of fetal, newborn, and adult guinea pigs. LÄS MER
4. Studies of Tight Junctions and Airway Surface Liquid in Airway Epithelium with Relevance to Cystic Fibrosis
Sammanfattning : Cystic fibrosis (CF) is a multi-organ autosomal recessive disease of fluid-transporting epithelia, due to a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is a cAMP-regulated Cl-channel involved in various regulatory processes. LÄS MER
5. Role of ion and water channels for lung growth in congenital diaphragmatic hernia
Sammanfattning : Early lung development is based on a continuous cross-talk of growth and transcription factors between the developing lung bud and the surrounding parenchyma. Throughout fetal life, pulmonary growth and differentiation depend on Cl- driven lung liquid secretion. LÄS MER