Sökning: "epigenetic"
Visar resultat 21 - 25 av 377 avhandlingar innehållade ordet epigenetic.
21. Epigenetic and Phenotypic Profiling of Urothelial Carcinoma
Sammanfattning : Precise spatial and temporal regulation of gene expression programs is a prerequisite for multicellular life. Since the discovery of DNA as the carrier of genetic information, a key question in biology has been how these hard coded instructions are read and regulated to maintain cellular and organismal homeostasis. LÄS MER
22. Depression : genetic, epigenetic and DNA biobank studies
Sammanfattning : Depression is a disease that has an estimated lifetime prevalence of ~15% and a heritability of ~36%. There is support for a heterogeneous etiology of depression, which includes: a) numerous genetic loci, b) various epigenetic contributors, and c) different environmental risk factors. LÄS MER
23. Genetic and epigenetic mechanisms in primary hyperparathyroidism
Sammanfattning : Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by abnormally excessive secretion of parathyroid hormone (PTH) and elevated serum calcium. PHPT patients can develop a wide range of complications affecting many body organs such as the skeleton, kidneys and heart. LÄS MER
24. Integration of epigenetic, transcriptomic and proteomic data
Sammanfattning : One of the scopes of Systems Biology is to propose mathematical models that best capture the dynamic behavior of intra-cellular processes. In this regard, the last two decades have brought up a shift in the field, with technological advances now allowing researchers to access a wide range of high-throughput technologies at an affordable cost. LÄS MER
25. Epigenetic changes and immunological features of chronic obstructive pulmonary disease
Sammanfattning : Background: Chronic obstructive pulmonary disease (COPD) is a heterogenous and chronic inflammatory syndrome with the lungs as its main target organ. Clinically, COPD is characterized by airflow limitation, chronic respiratory symptoms, and many extrapulmonary comorbidities. LÄS MER