Sökning: "enzymatic transformations"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden enzymatic transformations.

1. 1. Synthesis and asymmetric transformations of diols by enzyme- and ruthenium catalysis

   Författare :Karin Leijondahl; Jan-Erling Bäckvall; Kurt Faber; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dynamic kinetic asymmetric transformation; diols; enzymatic transformations; catalysis; ruthenium; transfer hydrogenation; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

   Sammanfattning : The major part of this thesis describes the synthesis of aliphatic secondary diols and the development of lipase- and ruthenium-catalyzed asymmetric transformations of these diols. Several acyclic 1,4-diols and 1,5-diols were synthesized, and by combining a lipase-catalyzed asymmetric transformation with a ruthenium-catalyzed epimerization, enantiomerically- and diastereomerically enriched diacetates were obtained. LÄS MER

3. 2. Enzyme- and Transition Metal-Catalyzed Asymmetric Transformations : Application of Enzymatic (D)KR in Enantioselective Synthesis

   Författare :Richard Lihammar; Jan-Erling Bäckvall; Wolfgang Kroutil; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Dynamic Kinetic Resolution; Kinetic Resolution; Enzyme Catalysis; Asymmetric Synthesis; organisk kemi; Organic Chemistry;

   Sammanfattning : Dynamic kinetic resolution (DKR) is a powerful method for obtaining compounds with high optical purity. The process relies on the combination of a kinetic resolution with an in situ racemization. LÄS MER

4. 3. Catalytic Stereoselective Formation of C–O, C–C and C–B Bonds : A Voyage from Asymmetric Reactions Enabled by Lipases to Stereoselective Palladium-Catalyzed Oxidative Transformations of Enallenes

   Författare :Bin Yang; Jan Bäckvall; Matthias Beller; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Synthesis; Enzymatic kinetic resolution; Palladium; Allenes; Oxidative Transformations; Ruthenium; organisk kemi; Organic Chemistry;

   Sammanfattning : This thesis has been focused on enzymatic kinetic resolutions and stereoselective oxidative transformations of enallenes catalyzed by PdII.In the first part of the thesis, a detailed discussion on Candida antarctica lipase B (CALB)-catalyzed kinetic resolution (KR) of δ-functionalized alkan-2-acetates is shown. LÄS MER

5. 4. Microbial and enzymatic syntheses of polymer building blocks through selective transformations of polyols and furans

   Författare :Mahmoud Sayed Ali Sayed; Bioteknik; []
   Nyckelord :Mycobacterium sp. MS1601; G. oxydans; oxidase; lipase; trimethylolpropane TMP ; 2; 2- bis hydroxymethyl butyric acid BHMB ; 5-hydroxymethyl furfural 5-HMF ; 5-hydroxymethyl-2-furan carboxylic acid HMFCA ; 2; 5-furandicarboxylic acid FDCA ; cyclic carbonate ; estrification; Biotransformation; polymer building blocks; product recovery; selective oxidation; bioprocess engneering; cell recycling; cell bleeding; DNA recombinant technology; in-silico analysis;

   Sammanfattning : AbstractTransition from fossil- to bio-based economy is a critical step towards reduction of greenhouse gas emissions and climate change, and hence for achievement of sustainable communities and environment. In order to be fossil-free, the chemical and material industry is in need of carbon-neutral building blocks from renewable resources for the diverse array of products that are currently produced from olefins and aromatics. LÄS MER

7. 5. Dynamic Systems : Enzymatic Synthesis, Exchange Reactions and Applications in Materials Science

   Författare :Yang Zhang; Olof Ramström; Mihail D. Barboiu; KTH; []
   Nyckelord :constitutional dynamic chemistry; reversible reactions; kinetic resolution; dynamic kinetic resolution; enzyme catalysis; lipase; asymmetric synthesis; racemization; oxazolidinone; organogel; enamine; nitroaldol reaction.;

   Sammanfattning : This thesis is divided into three parts, revolving around the developments of dynamic systems utilized in dynamic kinetic resolution (DKR) and constitutional dynamic chemistry (CDC).The first section gives an introduction to constitutional dynamics, the core concept of this thesis. LÄS MER