Sökning: "enterotoxin A SEA"
Visar resultat 6 - 10 av 18 avhandlingar innehållade orden enterotoxin A SEA.
6. Interplay between superantigens and immunoreceptors
Sammanfattning : This thesis deals with the interactions between superantigens and their receptors. Superantigens are proteins that are secreted by various bacteria, such as Staphylococcus aureus and Streptococcus pyogenes. Superantigens are able to cross-link T cells and antigen presenting cells by binding to the T cell receptor (TCR) and MHC class II. LÄS MER
7. The immunomodulatory function of staphylococcal superantigen on oral tolerance
Sammanfattning : Exposure to soluble proteins via the gut gives rise to systemic tolerance, a phenomenon called oral tolerance. Failure of oral tolerance results in allergy, a disease that has increased during the last decades in Western industrialized countries. The cause of this rapid increase is unknown. LÄS MER
8. Structural studies of metal-binding proteins revealing dynamic behaviour
Sammanfattning : The Mg2+ and Mn2+ structures of calbindin D9k have been determined and they reveal a conformational change compared to the structures of apo and (Ca2+)2-calbindin D9k. These findings are unique, since normally calcium and not magnesium is known to induce conformational changes of EF-hand proteins. LÄS MER
9. On the regulation of immune responses to dietary and self antigens
Sammanfattning : Regulatory mechanisms are necessary to avoid the misdirected aggressive immune responses responsible for the pathology seen in autoimmunity and allergy. Thymic-derived CD4+CD25+ regulatory T cells are indispensible for this regulation. We investigated if CD4+CD25+ Treg prevents auto-reactive responses in adult peripheral blood and cord blood. LÄS MER
10. Chronic kidney disease : a complex network of leukocyte dysfunction and inflammation
Sammanfattning : Chronic kidney disease (CKD) is a common medical condition with a prevalence of up to 13% worldwide. The insidious loss of renal function develops over time to reach end stage renal disease (ESRD) when the kidneys are unable to remove toxins and interventions such as dialysis or kidney transplantation are mandatory. LÄS MER