Sökning: "endotoxaemia"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet endotoxaemia.

  1. 1. Liver transplantation in man. Gastrointestinal perfusion and inflammatory response

    Författare :Ebbe Rønholm; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carbondioxide; complement activation; cytokines; endotoxaemia; hydrogen-ion concentration; liver transplantation; laser-Doppler flowmetry; PMN elastase; regional blood flow; reperfusion;

    Sammanfattning : Patients undergoing liver transplantation develop a systemic inflammatory response which eventually continues with development of a multiple organ dysfunction syndrome (MODS). Gastro-intestinal hypoxia or bacterial translocation has been proposed as the "motor" of MODS. LÄS MER

  3. 2. Nitric oxide and extravasation in endotoxaemia : an experimental study

    Författare :Kerstin Metcalf; Mikael Bodelsson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Background: Despite advances in intensive care the mortality of patients in septic shock is still high. In early stages the condition is characterised by circulatory failure that is a consequence of myocardial depression, vasodilatation with decreased sensitivity to catecholamine stimulation and increased loss of protein and fluid from the circulation. LÄS MER

  4. 3. Factors influencing splanchnic microcirculation in animal models of endotoxaemia

    Författare :Andreas Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Microcirculation;

    Sammanfattning : Even though severe sepsis and septic shock therapy has improved in recent years, mortality remains high (22-50%). Disturbances in splanchnic organ homeostasis and increases in gut permeability have long been presumed to contribute to systemic inflammation and multiple organ dysfunction syndrome in critical illness and septic shock. LÄS MER

  5. 4. Transvascular exchange and organ perfusion with reference to colloid and hypertonic solutions, and to endotoxaemia

    Författare :Staffan Holbeck; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; mannitol; microdialysis; intestine; hypertonic saline; gut; hydroxyethyl starch; gelatin; endotoxin; fluid therapy; dextran; albumin; capillary filtration coefficient; intensivvård; Anestesiologi; urea; Anaesthesiology; intensive care; SIRS; reflection coefficient;

    Sammanfattning : Changes in vascular permeability can immensely change plasma volume and affect the degree of oedema in the body. In diseases with an increased vascular permeability, adequate fluid therapy is of considerable importance to prevent hypovolaemia. LÄS MER

  7. 5. Pathophysiological, Inflammatory and Haemostatic Responses to Various Endotoxaemic Patterns : An Experimental Study in the Pig

    Författare :Miklós Lipcsey; Mats Eriksson; Jan Sjölin; Anders Larsson; Anders Bengtsson; Uppsala universitet; []
    Nyckelord :Anaesthesiology and intensive care; sepsis; animal model; cytokines; isoprostanes; endotoxic shock; pig; Anestesiologi och intensivvård;

    Sammanfattning : Septic shock is frequently seen in intensive care units and is associated with significant mortality. Endotoxin – a major mediator of the pathophysiologic responses – is released during lysis of Gram-negative bacteria. These responses can be mimicked in the endotoxaemic pig. LÄS MER